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纳武单抗治疗后IV期患者的挽救性胸腔镜切除术

Salvage thoracoscopic resection after nivolumab for stage IV.

作者信息

Hamaji Masatsugu, Ozasa Hiroaki, Yoshizawa Akihiko, Date Hiroshi

机构信息

Department of Thoracic Surgery, Kyoto University, Kyoto, Japan.

Department of Pulmonary Medicine, Kyoto University, Kyoto, Japan.

出版信息

Asian Cardiovasc Thorac Ann. 2020 May;28(4):216-218. doi: 10.1177/0218492320919477. Epub 2020 Apr 10.

DOI:10.1177/0218492320919477
PMID:32276540
Abstract

There are limited data on the surgical management of localized and residual diseases in patients with stage IV non-small-cell lung cancer that was treated with nivolumab. Herein, we present two patients who underwent salvage thoracoscopic resection for residual diseases (left lower lobectomy and paratracheal lymph node resection, respectively) after chemotherapy and immunotherapy for stage IV adenocarcinoma. The indications, intraoperative findings, and histopathological findings are discussed in this report.

摘要

关于接受纳武单抗治疗的IV期非小细胞肺癌患者局部和残留疾病的外科治疗数据有限。在此,我们介绍两名患者,他们在接受IV期腺癌化疗和免疫治疗后,因残留疾病分别接受了挽救性胸腔镜切除术(左下叶切除术和气管旁淋巴结切除术)。本报告讨论了手术指征、术中发现和组织病理学发现。

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Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.24-0096. Epub 2025 Mar 11.
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Characteristics and outcomes of salvage surgery after immune checkpoint inhibitor therapy for initially unresectable non-small cell lung cancer.免疫检查点抑制剂治疗初始不可切除非小细胞肺癌后挽救性手术的特征与结果
J Thorac Dis. 2024 Sep 30;16(9):6094-6100. doi: 10.21037/jtd-24-891. Epub 2024 Sep 24.