Leach D H, Caldwell S J, Ferguson J G
Department of Veterinary Anatomy, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
Acta Anat (Basel). 1988;133(3):234-46. doi: 10.1159/000146646.
The synovial intima from the antebrachiocarpal joint of 4-month-old calves was between 1 and 3 cells in thickness and did not have a basal lamina. Numerous areas of the intimal matrix were in direct contact with the joint lumen. The synovial membrane was comprised mainly of A-type synoviocytes usually located adjacent to the joint lumen. These cells were characterized by numerous filopodia (or lamellipodia), large, empty-appearing vacuoles, numerous lysosomes, large vacuoles containing granular material separated from the vacuolar membrane by a radiolucent band, and coated micropinocytotic vesicles. Smooth micropinocytotic vesicles were seen only rarely in these cells. In contrast, B-type cells had few filopodia, numerous smooth micropinocytotic vesicles, few coated micropinocytotic vesicles, a well-developed Golgi apparatus and rough endoplasmic reticulum, mitochondria that were longer and had a denser matrix than that of A cell mitochondria, and surprisingly, only few maturing or fully formed secretory granules. A distinct intermediate (C or AB) type synoviocyte could not be unequivocally identified. Desmosome-like structures were present between synoviocytes, although it was considered questionable if these were true intercellular junctions. No other junctions were present.
4月龄犊牛腕关节的滑膜内膜厚度为1至3个细胞，无基膜。内膜基质的许多区域与关节腔直接接触。滑膜主要由通常位于关节腔附近的A型滑膜细胞组成。这些细胞的特征是有许多丝状伪足（或片状伪足）、大的、看似空泡的液泡、许多溶酶体、含有颗粒物质的大液泡，颗粒物质与液泡膜之间有一条透光带，还有被膜微胞饮小泡。在这些细胞中很少见到光滑微胞饮小泡。相比之下，B型细胞丝状伪足较少，有许多光滑微胞饮小泡，被膜微胞饮小泡较少，高尔基体和粗面内质网发达，线粒体比A型细胞的线粒体更长且基质更致密，令人惊讶的是，成熟或完全形成的分泌颗粒很少。未明确鉴定出明显的中间型（C型或AB型）滑膜细胞。滑膜细胞之间存在类似桥粒的结构，尽管这些是否为真正的细胞间连接存在疑问。不存在其他连接。
