Urology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Urology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Urology. 2020 Jul;141:55-59. doi: 10.1016/j.urology.2020.03.019. Epub 2020 Apr 8.
Some recent studies evaluated the introduction of diffusion-weighted magnetic resonance imaging (DW-MRI) in the diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC).
To evaluate whether DW-MRI can contribute to noninvasive diagnosis of BPS/IC. The agreement between two raters (2 radiologists involved in the study) was also evaluated, the relevance of the "operator-dependent" factor defined.
Twenty-two female patients with a diagnosis of BPS-IC were recruited and performed DW-MRI. The same investigation was also performed in 20 patients with pelvic gynecological diseases and no BPS-IC.
A significant difference was found between BPS-IC and no-BPS-IC since 17 out of 22 subjects of the first group were positive, compared to 3 out of 20 no-IC subjects, with a P value of .001 to highlight the statistical significance. The sensitivity of the exam was 77%, while the specificity was 85%. There was good agreement between the 2 raters in the evaluation of MRI results.
DW-MRI helps to obtain a noninvasive diagnosis of BPS/IC, by providing useful information on the choice of which patients may be more appropriately submitted to cystoscopy and bladder biopsy.
一些最近的研究评估了在诊断膀胱疼痛综合征/间质性膀胱炎（BPS/IC）中引入弥散加权磁共振成像（DW-MRI）的效果。
评估 DW-MRI 是否有助于 BPS/IC 的无创诊断。还评估了两位评估者（参与研究的 2 位放射科医生）之间的一致性，定义了“操作者依赖”因素的相关性。
招募了 22 名女性 BPS-IC 诊断患者进行 DW-MRI。还对 20 名患有盆腔妇科疾病且无 BPS-IC 的患者进行了相同的检查。
由于第一组 22 名受试者中有 17 名呈阳性，而无 IC 组的 20 名受试者中只有 3 名呈阳性，差异具有统计学意义（P 值<.001）。该检查的灵敏度为 77%，特异性为 85%。两位评估者在 MRI 结果的评估中有很好的一致性。
DW-MRI 通过提供有关哪些患者可能更适合接受膀胱镜检查和膀胱活检的有用信息，有助于对 BPS/IC 进行无创诊断。
