Recyclable Eu functionalized Hf-MOF fluorescent probe for urinary metabolites of some organophosphorus pesticides.

A luminescent metal-organic framework Eu functionalized Hf-MOF (Eu@1) is designed through post-synthesis modification (PSM) and utilized as a probe for detecting p-nitrophenol (PNP, the urinary metabolite of parathion, methyl-parathion and EPN) and 3-methyl-4-nitrophenol (PNMC, the urinary metabolite of fenitrothion). The apparent quenching effect in urine is observed from the Eu@1 with the addition of organophosphorus metabolites. The fluorescent probe has several appealing merits, such as high selectivity, excellent sensitivity (0.36 μg mL for PNP, 0.41 μg mL for PNMC), fast response time (less than 1 min) and easy preparation. Linear correlation between the fluorescence intensity of Eu@1 and the concentration of PNP and PNMC are from 0.005 to 0.15 mg mL and 0.005-0.30 mg mL, respectively. Furthermore, this fluorescent material also demonstrated the possibility for recycling. It is a prominent candidate for potential application in personalized monitoring the internal dose of human exposure to some organophosphorus pesticides.