Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX 75390, USA.
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX 75390, USA.
Immunol Allergy Clin North Am. 2020 May;40(2):371-383. doi: 10.1016/j.iac.2019.12.008. Epub 2020 Jan 22.
Chronic rhinosinusitis (CRS) is present in up to 100% of patients with cystic fibrosis (CF). CF-associated CRS is particularly recalcitrant, and sinus disease can have important implications in the health of the lower airways and overall quality of life in these patients. Both medical and surgical management play important roles in treating CF-associated CRS, but guidelines are lacking. This review summarizes the current literature on both medical and surgical management of this disease to provide an up-to-date analysis and recommendations on the treatment of CF-associated CRS.
慢性鼻-鼻窦炎（CRS）在囊性纤维化（CF）患者中高达 100%存在。CF 相关 CRS 尤其顽固，鼻窦疾病对这些患者的下呼吸道健康和整体生活质量有重要影响。医学和手术管理在治疗 CF 相关 CRS 中都起着重要作用，但缺乏指南。本综述总结了目前关于该疾病的医学和手术管理的文献，提供了对 CF 相关 CRS 治疗的最新分析和建议。
