From the Division of Neurology, Department of Medicine (M.V.V., F.L.S.), University of Toronto, Canada.
Institute of Health Policy, Management and Evaluation (M.V.V., A.L., P.C.A., M.K.K.), University of Toronto, Canada.
Stroke. 2020 May;51(5):1555-1562. doi: 10.1161/STROKEAHA.119.027791. Epub 2020 Apr 13.
Background and Purpose- Immigrants to high-income countries have a lower incidence of stroke compared with long-term residents; however, little is known about the care and outcomes of stroke in immigrants. Methods- We used linked clinical and administrative data to conduct a retrospective cohort study of adults seen in the emergency department or hospitalized with ischemic stroke or transient ischemic attack between July 1, 2003, and April 1, 2013, and included in the provincial stroke registry. We ascertained immigration status using immigration records and compared processes of stroke care delivery between immigrants (defined as those immigrating after 1985) and long-term residents. In the subgroup with ischemic stroke, we calculated inverse probability treatment weight (IPTW)-adjusted risk ratios for disability on discharge (modified Rankin Scale score of 3 to 5), accounting for demographic characteristics and comorbid conditions to compare outcomes between immigrants and long-term residents. Results- We included 34 987 patients with ischemic stroke or transient ischemic attack, of whom 2649 (7.6%) were immigrants. Immigrants were younger than long-term residents at the time of stroke/transient ischemic attack (median age 67 years versus 76 years; <0.001). In the subgroup with ischemic stroke, there were no differences in stroke care delivery, except that a higher proportion of immigrants received thrombolysis than long-term residents (21.2% versus 15.5%; <0.001). Immigrants with ischemic stroke had a higher adjusted risk of being disabled on discharge (adjusted risk ratio, 1.18; 95% CI, 1.13-1.22) compared to long-term residents. Conclusions- Stroke care is similar in Canadian immigrants and long-term residents. Future research is needed to confirm the observed association between immigration status and disability after stroke and to identify factors underlying the association.
背景与目的-与长期居民相比,移民到高收入国家的人群中风发病率较低;然而,对于移民中风的护理和结局知之甚少。方法-我们使用关联的临床和行政数据,对 2003 年 7 月 1 日至 2013 年 4 月 1 日期间在急诊室就诊或因缺血性中风或短暂性脑缺血发作住院并纳入省级中风登记处的成年人进行了回顾性队列研究。我们通过移民记录确定移民身份,并比较移民(定义为 1985 年后移民)和长期居民的中风护理提供过程。在缺血性中风亚组中,我们计算了基于逆概率处理权重(Inverse Probability Treatment Weight,IPTW)调整的残疾出院风险比(改良 Rankin 量表评分 3 至 5),以考虑人口统计学特征和合并症,比较移民和长期居民的结局。结果-我们纳入了 34987 例缺血性中风或短暂性脑缺血发作患者,其中 2649 例(7.6%)为移民。移民在中风/短暂性脑缺血发作时比长期居民年轻(中位数年龄 67 岁对 76 岁;<0.001)。在缺血性中风亚组中,除了接受溶栓治疗的移民比例高于长期居民(21.2%对 15.5%;<0.001)外,中风护理提供没有差异。与长期居民相比,缺血性中风的移民出院时残疾的调整风险更高(调整风险比,1.18;95%置信区间,1.13-1.22)。结论-加拿大移民和长期居民的中风护理相似。需要进一步研究来确认移民身份与中风后残疾之间的观察到的关联,并确定关联的潜在因素。