Fine Lina
Swedish Sleep Medicine, 550 17 Avenue, Seattle, WA 98122, USA.
Phys Med Rehabil Clin N Am. 2020 May;31(2):255-264. doi: 10.1016/j.pmr.2020.01.003. Epub 2020 Mar 10.
Sleep management is essential to effective treatment of pain symptoms. Identification of the precise nature of sleep complaint, awareness of patient's age and co-morbid conditions and choice of the hypnotic medication class can help guide treatment approach. In addition to benzodiazepine and non-benzodiazepine medications acting at the GABA receptor, novel approaches, including orexin receptor agonists, may be safer and more promising pharmacologic approaches. Pharmacologic interventions, when used cautiously for a limited period of time and in complement with behavioral and cognitive approaches, can serve to improve sleep quality and significantly help in management of pain.
睡眠管理对于有效治疗疼痛症状至关重要。明确睡眠问题的确切性质、了解患者的年龄和共病情况以及选择催眠药物类别有助于指导治疗方法。除了作用于GABA受体的苯二氮䓬类和非苯二氮䓬类药物外，包括食欲素受体激动剂在内的新方法可能是更安全、更有前景的药物治疗方法。当在有限的时间内谨慎使用并与行为和认知方法相结合时，药物干预有助于改善睡眠质量，并显著有助于疼痛管理。
