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美国超过十年时间内全关节置换术后感染的清创术、抗生素和植入物保留的利用情况。

Utilization of Debridement, Antibiotics, and Implant Retention for Infection After Total Joint Arthroplasty Over a Decade in the United States.

机构信息

Department of Orthopedic Surgery, Adult Reconstruction and Joint Replacement, Hospital for Special Surgery, New York, NY.

Department of Medicine, Division of Infectious Disease, Hospital for Special Surgery, New York, NY.

出版信息

J Arthroplasty. 2020 Aug;35(8):2210-2216. doi: 10.1016/j.arth.2020.03.029. Epub 2020 Mar 21.

Abstract

BACKGROUND

Reported clinical outcomes have varied for debridement, antibiotics, and implant retention (DAIR) and little is known regarding trends in utilization. We sought to evaluate the rate of DAIR utilization for total knee arthroplasty (TKA) and total hip arthroplasty (THA) periprosthetic joint infection (PJI) over a decade and clinical factors associated with these trends.

METHODS

A retrospective study of primary TKAs and THAs was performed using Medicare data from 2005 to 2014 using the PearlDiver database platform. Current Procedural Technology and International Classification of Diseases Ninth Edition codes identified patients who underwent a surgical revision for PJI, whether revision was a DAIR, as well as associated clinical factors including timing from index arthroplasty.

RESULTS

The proportion of revision TKAs and THAs performed using DAIR was 27% and 12% across all years, respectively. This proportion varied by year for TKAs and THAs with a linear trend toward increasing relative use of DAIR estimated at 1.4% and 0.9% per year (P < .001; P < .001). DAIR for TKA and THA performed within 90 days increased at a faster rate, 3.4% and 2.1% per year (P < .001; P < .001). Trends over time in TKA DAIRs showed an association with Elixhauser Comorbidity Index (ECI), 0-5 group increasing at 2.0% per year (P = .03) and patients >85 years (P = .04).

CONCLUSION

The proportion of revision arthroplasty cases for PJI managed with DAIR has been increasing over time in the United States, with the most substantial increase seen <90 days from index arthroplasty. Age, gender, and ECI had a minimal association with this trend, except in the TKA population >85 years and in those with a very low ECI score.

摘要

背景

清创术、抗生素和植入物保留(DAIR)的报道临床结果各不相同,关于其使用趋势知之甚少。我们旨在评估十年来全膝关节置换术(TKA)和全髋关节置换术(THA)治疗假体周围关节感染(PJI)的 DAIR 使用率以及与这些趋势相关的临床因素。

方法

使用 PearlDiver 数据库平台,对 2005 年至 2014 年期间 Medicare 数据进行了 TKA 和 THA 的回顾性研究。使用当前的手术技术和国际疾病分类第九版代码确定了接受 PJI 手术翻修的患者,无论翻修是否为 DAIR,以及包括从索引关节置换术开始的相关临床因素。

结果

所有年份中,使用 DAIR 进行 TKA 和 THA 翻修的比例分别为 27%和 12%。TKA 和 THA 的这一比例因年份而异,DAIR 的相对使用量呈线性趋势,每年分别增加 1.4%和 0.9%(P<0.001;P<0.001)。TKA 和 THA 在 90 天内进行的 DAIR 增加速度更快,每年分别增加 3.4%和 2.1%(P<0.001;P<0.001)。TKA 的 DAIR 随时间的变化趋势与 Elixhauser 合并症指数(ECI)有关,0-5 组每年增加 2.0%(P=0.03),85 岁以上患者(P=0.04)。

结论

在美国,随着时间的推移,PJI 管理中使用 DAIR 的翻修关节置换病例比例一直在增加,尤其是在指数关节置换术后 90 天内。年龄、性别和 ECI 与这一趋势有最小的关联,除了 TKA 患者中 85 岁以上和 ECI 评分非常低的患者。

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