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人工关节感染翻修全膝关节置换术发生率的时间趋势

Temporal Trends in the Rate of Revision Total Knee Arthroplasty for Prosthetic Joint Infection.

作者信息

Bass Anne R, Mehta Bella, Sculco Peter K, Zhang Yi, Do Huong T, Glaser Katharine Kayla J, Aude Carlos, Carli Alberto V, Figgie Mark P, Goodman Susan M

机构信息

Division of Rheumatology, Department of Medicine, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, USA.

Department of Orthopedics, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, USA.

出版信息

Arthroplast Today. 2024 Jul 3;28:101442. doi: 10.1016/j.artd.2024.101442. eCollection 2024 Aug.

Abstract

BACKGROUND

Perioperative practices have been introduced over the last decade to decrease the risk of periprosthetic joint infection (PJI). We sought to determine whether rates of revision total knee arthroplasty (TKA) for PJI decreased during the period 2006-2016.

METHODS

This observational cohort study used data from the New York Statewide Planning and Research Cooperative System to identify patients undergoing TKA in 2006-2016. Data through 2017 were used to determine if patients underwent revision TKA for PJI (including debridement, antibiotics and implant retention) within 1 year of the primary surgery. A generalized estimating equation model, clustered by hospital, was used to examine the impact of time on likelihood of revision TKA for PJI.

RESULTS

In 2006-2016, 233,165 primary TKAs performed were included. Mean age was 66.1 (standard deviation 10.3) years, and 65% were women. Overall, 0.5% of the patients underwent revision TKA for PJI within 1 year of surgery. The generalized estimating equation model showed that for primary TKA performed in 2006-2013, year of surgery did not impact the likelihood of revision TKA for PJI (odds ratio 1.00, 95% confidence interval 0.97-1.03,  = .9221), but that for primary TKA performed in 2014-2016, the likelihood decreased by year (odds ratio 0.76, 95% confidence interval 0.66-0.88,  = .0002).

CONCLUSIONS

The likelihood of revision TKA for PJI was stable from 2006 to 2013 but declined during the period 2014-2016 across patient and hospital categories. This decline could be due to infection mitigation strategies or other unmeasured factors.

摘要

背景

在过去十年中引入了围手术期措施以降低人工关节周围感染(PJI)的风险。我们试图确定2006年至2016年期间因PJI进行翻修全膝关节置换术(TKA)的发生率是否有所下降。

方法

这项观察性队列研究使用了纽约州全州规划与研究合作系统的数据,以识别2006年至2016年期间接受TKA的患者。利用截至2017年的数据来确定患者在初次手术后1年内是否因PJI接受了翻修TKA(包括清创、抗生素治疗和保留植入物)。采用按医院聚类的广义估计方程模型来检验时间对因PJI进行翻修TKA可能性的影响。

结果

2006年至2016年期间,共纳入233,165例初次TKA。平均年龄为66.1(标准差10.3)岁,65%为女性。总体而言,0.5%的患者在手术后1年内因PJI接受了翻修TKA。广义估计方程模型显示,对于2006年至2013年进行的初次TKA,手术年份不影响因PJI进行翻修TKA的可能性(优势比1.00,95%置信区间0.97 - 1.03,P = 0.9221),但对于2014年至2016年进行的初次TKA,可能性逐年下降(优势比0.76,95%置信区间0.66 - 0.88,P = 0.0002)。

结论

2006年至2013年期间,因PJI进行翻修TKA的可能性保持稳定,但在2014年至2016年期间,在不同患者和医院类别中均有所下降。这种下降可能归因于感染缓解策略或其他未测量的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398f/11283064/2b78abd164b8/gr1.jpg

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