Hanke Alexander A, Bartlau Jan, Flöricke Felix, Przemeck Michael, Horstmann Hauke, Weber-Spickschen Thomas S, Sieg Lion, Schumacher Carsten
Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule, Hannover, Germany.
Institut für Sportsmedizin, Medizinische Hochschule, Hannover, Germany.
J Orthop. 2020 Mar 25;22:22-28. doi: 10.1016/j.jor.2020.03.032. eCollection 2020 Nov-Dec.
Perioperative coagulation monitoring and transfusions were evaluated.
70 cases were included. Time points: before (PRE), after surgery (POST), day 1, day 3, day 7. Standard and patient near tests were assessed. Groups were: Transfused (TG); Control (CG).
23 patients were transfused (TG), 47 were not (CG). PRE haemoglobin was reduced, coagulation time (CT) was prolonged in TG. FIBTEM decrease was higher in TG. Leukocytes were elevated in TG. ASPI decreased, TRAP and ADP aggregability increased in both groups.
CT, haemoglobin and fibrinogen were associated with transfusion. TRAP and ADP aggregability increased and could account for thromboembolism.
评估围手术期凝血监测及输血情况。
纳入70例患者。时间点包括：术前（PRE）、术后（POST）、第1天、第3天、第7天。评估标准检测和患者床边检测。分组为：输血组（TG）；对照组（CG）。
23例患者接受输血（TG），47例未输血（CG）。输血组术前血红蛋白降低，凝血时间（CT）延长。输血组FIBTEM降低更明显。输血组白细胞升高。两组的ASPI均降低，TRAP和ADP聚集性均增加。
凝血时间、血红蛋白和纤维蛋白原与输血有关。TRAP和ADP聚集性增加，可能是血栓栓塞的原因。
