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哥伦比亚儿童的原发性免疫缺陷

Primary immunodeficiency in Colombian children.

作者信息

Núñez R M

机构信息

Universidad de Caldas, Facultad de Medicina, Departamento de Pediatría, Hospital Infantil Universitario, Manizales, Galdas, Colombia.

出版信息

Allergol Immunopathol (Madr). 1988 Jul-Aug;16(4):273-5.

PMID:3228048
Abstract

Eighty-three patients with diagnosis of immunodeficiency were studied, antibody deficiency disorders were the most common 74.6%, abnormalities of unspecific mechanisms in 13.3% and deficiencies of cell mediated immunity in 9.6% of patients. Selective IgA deficiency was the most common of the humoral defects, 28 patients, the others were IgM and IgG selectives deficiency. The mortality was 6%, specially in patients with cellular deficiency. Immunodeficiencies are one of most common genetic diseases, needing appropriate diagnosis, treatment and developing centers with advanced technology.

摘要

对83例诊断为免疫缺陷的患者进行了研究,抗体缺陷疾病最为常见,占74.6%,非特异性机制异常占13.3%,细胞介导免疫缺陷占9.6%。选择性IgA缺乏是最常见的体液缺陷,有28例患者,其他为IgM和IgG选择性缺乏。死亡率为6%,特别是细胞免疫缺陷的患者。免疫缺陷是最常见的遗传疾病之一,需要进行适当的诊断、治疗,并建立拥有先进技术的诊疗中心。

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