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髓内圆锥肿瘤手术期间的球海绵体反射监测

Bulbocavernosus Reflex Monitoring During Intramedullary Conus Tumor Surgery.

作者信息

Overzet Kathryn, Jahangiri Faisal R, Funk Robert

机构信息

Neurophysiology, Axis Neuromonitoring, Richardson, USA.

Neurophysiology, Global Innervation, Dallas, USA.

出版信息

Cureus. 2020 Mar 10;12(3):e7233. doi: 10.7759/cureus.7233.

DOI:10.7759/cureus.7233
PMID:32280574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7145379/
Abstract

A T10 to L2 spinal cord tumor exploration and biopsy was performed with intraoperative neurophysiological monitoring (IONM) on a 75-year-old male diagnosed with an intradural intramedullary appearing spinal cord lesion with no other lesions in the central nervous system, chest, abdomen or pelvis. Intraoperative neurophysiology consisted of transcranial electrical motor evoked potentials (TCeMEPs), somatosensory evoked potentials (SSEPs), triggered and spontaneous electromyography (S-EMG, T-EMG), bulbocavernosus reflex (BCR) and train of four (TOF) monitoring. Loss of BCR responses during conus exposure and identification were resolved with multiple small pauses in manipulation throughout the procedure. T-EMG mapping aided in identification and avoiding the removal of nervous tissue. Postoperatively the patient experienced some mild weakness in his left foot and leg that correlated with a significant amplitude drop in the left abductor hallucis TCeMEP. By the following day, the patient was almost back to preoperative baseline. The patient's bowel and bladder function were preserved, consistent with final BCR recordings. The patient was discharged to rehabilitation postoperatively. Pathology results indicated glioblastoma. This case study demonstrates the utility of a multimodality approach with bulbocavernosus reflex and urethral sphincter monitoring to optimize intraoperative data to the surgeon during conus tumor surgeries.

摘要

对一名75岁男性进行了T10至L2脊髓肿瘤探查和活检,术中进行神经生理监测(IONM)。该男性被诊断为硬脊膜内髓内脊髓病变,中枢神经系统、胸部、腹部或骨盆无其他病变。术中神经生理学监测包括经颅电运动诱发电位(TCeMEP)、体感诱发电位(SSEP)、触发和自发肌电图(S-EMG、T-EMG)、球海绵体反射(BCR)和四个成串刺激(TOF)监测。在圆锥暴露和识别过程中BCR反应消失,通过在整个手术过程中多次短暂暂停操作得以解决。T-EMG图谱有助于识别和避免切除神经组织。术后患者左脚和腿部出现轻度无力,与左侧拇展肌TCeMEP的显著波幅下降相关。到第二天,患者几乎恢复到术前基线水平。患者的肠道和膀胱功能得以保留,与最终的BCR记录一致。术后患者出院接受康复治疗。病理结果显示为胶质母细胞瘤。本病例研究证明了在圆锥肿瘤手术中采用球海绵体反射和尿道括约肌监测的多模态方法,可为外科医生优化术中数据的实用性。

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本文引用的文献

1
Intraoperative Triggered Electromyography Recordings from the External Urethral Sphincter Muscles During Spine Surgeries.脊柱手术中尿道外括约肌的术中触发肌电图记录
Cureus. 2019 Jun 10;11(6):e4867. doi: 10.7759/cureus.4867.
2
Motor Evoked Potential Recordings from the Urethral Sphincter Muscles (USMEPs) during Spine Surgeries.脊柱手术期间尿道括约肌肌肉的运动诱发电位记录(USMEPs)
Neurodiagn J. 2019;59(1):34-44. doi: 10.1080/21646821.2019.1572375.
3
Intraoperative feasibility of bulbocavernosus reflex monitoring during untethering surgery in infants and children.
婴幼儿脊髓栓系松解手术中球海绵体反射监测的术中可行性
J Clin Monit Comput. 2019 Feb;33(1):155-163. doi: 10.1007/s10877-018-0127-2. Epub 2018 Mar 8.
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The importance of the bulbocavernosus reflex.球海绵体肌反射的重要性。
Spinal Cord Ser Cases. 2018 Jan 10;4:2. doi: 10.1038/s41394-017-0012-0. eCollection 2018.
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Multimodal intraoperative monitoring during intramedullary spinal cord tumor surgery.脊髓髓内肿瘤手术中的多模式术中监测
Acta Neurochir (Wien). 2015 Dec;157(12):2149-55. doi: 10.1007/s00701-015-2598-y. Epub 2015 Oct 7.
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The value of intraoperative neurophysiological monitoring for microsurgical removal of conus medullaris lipomas: a 12-year retrospective cohort study.术中神经生理监测在显微手术切除圆锥脂肪瘤中的价值:一项12年的回顾性队列研究
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Intraoperative recording of the bulbocavernosus reflex.球海绵体反射的术中记录
J Clin Neurophysiol. 2014 Aug;31(4):313-22. doi: 10.1097/WNP.0000000000000054.
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Intraoperative neurophysiology of the conus medullaris and cauda equina.脊髓圆锥和马尾的术中神经生理学
Childs Nerv Syst. 2010 Feb;26(2):247-53. doi: 10.1007/s00381-009-1020-6. Epub 2009 Nov 11.
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Intramedullary spinal cord tumor surgery: can we do it without intraoperative neurophysiological monitoring?脊髓髓内肿瘤手术:不进行术中神经生理监测我们能做吗?
Childs Nerv Syst. 2010 Feb;26(2):241-5. doi: 10.1007/s00381-009-1022-4. Epub 2009 Nov 10.
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