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髓内圆锥肿瘤手术期间的球海绵体反射监测

Bulbocavernosus Reflex Monitoring During Intramedullary Conus Tumor Surgery.

作者信息

Overzet Kathryn, Jahangiri Faisal R, Funk Robert

机构信息

Neurophysiology, Axis Neuromonitoring, Richardson, USA.

Neurophysiology, Global Innervation, Dallas, USA.

出版信息

Cureus. 2020 Mar 10;12(3):e7233. doi: 10.7759/cureus.7233.

Abstract

A T10 to L2 spinal cord tumor exploration and biopsy was performed with intraoperative neurophysiological monitoring (IONM) on a 75-year-old male diagnosed with an intradural intramedullary appearing spinal cord lesion with no other lesions in the central nervous system, chest, abdomen or pelvis. Intraoperative neurophysiology consisted of transcranial electrical motor evoked potentials (TCeMEPs), somatosensory evoked potentials (SSEPs), triggered and spontaneous electromyography (S-EMG, T-EMG), bulbocavernosus reflex (BCR) and train of four (TOF) monitoring. Loss of BCR responses during conus exposure and identification were resolved with multiple small pauses in manipulation throughout the procedure. T-EMG mapping aided in identification and avoiding the removal of nervous tissue. Postoperatively the patient experienced some mild weakness in his left foot and leg that correlated with a significant amplitude drop in the left abductor hallucis TCeMEP. By the following day, the patient was almost back to preoperative baseline. The patient's bowel and bladder function were preserved, consistent with final BCR recordings. The patient was discharged to rehabilitation postoperatively. Pathology results indicated glioblastoma. This case study demonstrates the utility of a multimodality approach with bulbocavernosus reflex and urethral sphincter monitoring to optimize intraoperative data to the surgeon during conus tumor surgeries.

摘要

对一名75岁男性进行了T10至L2脊髓肿瘤探查和活检,术中进行神经生理监测(IONM)。该男性被诊断为硬脊膜内髓内脊髓病变,中枢神经系统、胸部、腹部或骨盆无其他病变。术中神经生理学监测包括经颅电运动诱发电位(TCeMEP)、体感诱发电位(SSEP)、触发和自发肌电图(S-EMG、T-EMG)、球海绵体反射(BCR)和四个成串刺激(TOF)监测。在圆锥暴露和识别过程中BCR反应消失,通过在整个手术过程中多次短暂暂停操作得以解决。T-EMG图谱有助于识别和避免切除神经组织。术后患者左脚和腿部出现轻度无力,与左侧拇展肌TCeMEP的显著波幅下降相关。到第二天,患者几乎恢复到术前基线水平。患者的肠道和膀胱功能得以保留,与最终的BCR记录一致。术后患者出院接受康复治疗。病理结果显示为胶质母细胞瘤。本病例研究证明了在圆锥肿瘤手术中采用球海绵体反射和尿道括约肌监测的多模态方法,可为外科医生优化术中数据的实用性。

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