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解剖外修复主动脉十二指肠瘘后主动脉残端破裂的血管内治疗:一例病例报告及文献复习

Endovascular treatment of aortic stump blow-out after extra-anatomical repair of aortoduodenal fistula: a case report and review of literature.

作者信息

Beijer E, Scholtes V P W, Moerbeek P, Coveliers H M E, Lely R J, Hoksbergen A W J

机构信息

Department of Surgery, Amsterdam University Medical Centre, location VUmc, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.

Department of Surgery, General City Hospital, Aalst, Belgium.

出版信息

CVIR Endovasc. 2020 Apr 13;3(1):21. doi: 10.1186/s42155-020-00111-8.

Abstract

BACKGROUND

An aortoduodenal fistula (ADF) is an unusual, but serious complication following surgical or endovascular aortic repair. The optimal treatment for ADF consists of removal of the infected graft with in situ or extra-anatomical repair and is associated with high mortality. Part of this mortality is caused by re-bleeding or aortic stump ruptures. Classical treatment of an aortic stump rupture involves immediate re-laparotomy, removal of infected tissue, aortic stump formation and reinforcement with soft tissue flaps. However, this invasive treatment is often difficult to perform and the condition of the patient frequently requires a more rapid response. We describe a case in which an aortic stump rupture was treated endovascularly by using an Amplatzer® Vascular Plug, which successfully stopped the bleeding.

CASE PRESENTATION

This report describes a 67-year-old man who was presented with persistent duodenal leakage (due to secondary duodenal perforation) after resection and open in-situ repair of an infected aorto-bi-femoral prosthetic graft. An extra-anatomical reconstruction was performed with an axillo-bi-femoral bypass, followed by excision of the prosthesis, aortic stump formation, partial duodenal resection and duodenojejunal reconstruction. Twelve weeks later, sudden severe hematemesis with severe hemodynamic instability occurred. Computed tomography angiography showed extravasation of blood from the aortic stump into the duodenal loop. Endovascular treatment of the aortic stump blow-out with an Amplatzer® Vascular Plug was performed, which successfully stopped the bleeding and stabilized the patient. The duodenal fistula was treated conservatively. Three months later, the patient was discharged to a rehabilitation clinic in a good clinical condition. The patient was still alive after a follow-up of 4 years.

CONCLUSIONS

Rapid treatment is requested in cases of aortic stump rupture. Re-laparotomy is practically never the most suitable solution and most of these aortic stump ruptures are fatal. Endovascular treatment could be a suitable alternative. Whether the endovascular treatment of aortic stump rupture is a definitive treatment or a bridge to surgery remains to be elucidated.

摘要

背景

主动脉十二指肠瘘(ADF)是外科手术或血管内主动脉修复术后一种罕见但严重的并发症。ADF的最佳治疗方法是原位或解剖外修复并移除感染的移植物,且死亡率较高。部分死亡原因是再次出血或主动脉残端破裂。主动脉残端破裂的传统治疗方法包括立即再次剖腹手术、清除感染组织、形成主动脉残端并用软组织瓣加固。然而,这种侵入性治疗往往难以实施,且患者的病情常常需要更快速的应对措施。我们描述了一例使用Amplatzer®血管封堵器进行血管内治疗主动脉残端破裂并成功止血的病例。

病例介绍

本报告描述了一名67岁男性,在切除并原位开放修复感染的主动脉双股人工血管移植物后出现持续性十二指肠渗漏(由于继发性十二指肠穿孔)。进行了腋双股旁路的解剖外重建,随后切除假体、形成主动脉残端、部分十二指肠切除及十二指肠空肠重建。十二周后,突然发生严重呕血并伴有严重血流动力学不稳定。计算机断层血管造影显示血液从主动脉残端渗入十二指肠袢。使用Amplatzer®血管封堵器对主动脉残端破裂进行血管内治疗,成功止血并使患者病情稳定。十二指肠瘘采用保守治疗。三个月后,患者以良好的临床状态出院至康复诊所。随访4年后患者仍然存活。

结论

主动脉残端破裂病例需要快速治疗。再次剖腹手术几乎从来都不是最合适的解决方案,而且大多数此类主动脉残端破裂是致命的。血管内治疗可能是一种合适的替代方法。主动脉残端破裂的血管内治疗是确定性治疗还是手术的桥梁,仍有待阐明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e88/7152582/c78b93033922/42155_2020_111_Fig1_HTML.jpg

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