Fragile site in chromosome 12 in a patient with two miscarriages.
作者信息
Stetten G, Sroka B, Norbury-Glaser M, Corson V L
机构信息
Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, Maryland 21205.
出版信息
Am J Med Genet. 1988 Nov;31(3):521-5. doi: 10.1002/ajmg.1320310306.
PMID:3228135
Abstract
A heritable fragile site at 12q13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate-sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.
摘要
Zotero 插件