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经鼻内镜视神经管减压术治疗间接性外伤性视神经病变的预后因素分析

Analysis of Prognostic Factors for the Indirect Traumatic Optic Neuropathy Underwent Endoscopic Transnasal Optic Canal Decompression.

作者信息

Lin Jingquan, Hu Wanglu, Wu Qun, Yi Jianhua, Liu Zhihai, Zhou Guangju, Ma Feiqiang, Zhang Jianmin, Yan Wei

机构信息

Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine.

Department of Emergency Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine.

出版信息

J Craniofac Surg. 2020 Jul-Aug;31(5):1266-1269. doi: 10.1097/SCS.0000000000006443.

Abstract

OBJECTIVE

This study aimed to investigate the clinical outcomes of endoscopic transnasal optic canal decompression (ETOCD) for patients with indirect traumatic optic neuropathy (TON) and identify the relevant prognostic factors.

METHODS

Seventy-two indirect TON patients who underwent ETOCD surgery from August 2017 to May 2019 were analyzed retrospectively. The paired t-test was used to compare the visual acuity (VA) before and after ETOCD, and multiple linear regression analysis was used to distinguish the potential prognostic factors.

RESULTS

Among the patients analyzed, postoperative VA (-2.87 ± 0.19) was significantly higher than the preoperative VA (-3.92 ± 0.13) (P < 0.05). Multiple linear regression analysis models showed that poor initial VA and longer time to surgery were independent risk factors for VA prognosis (P < 0.05), but surgical time alone was significantly associated with the improvement degree of visual acuity (IDVA) (P < 0.05). Optic canal fracture, orbital fracture, and hemorrhage within the ethmoid and/or sphenoid sinus were not significantly correlated with IDVA and VA prognosis (P > 0.05).

CONCLUSIONS

ETOCD surgery could salvage VA impairment in patients with indirect TON. A better initial VA indicates better final VA outcomes after surgery. Additionally, shorter time to surgery implies better VA prognosis and higher IDVA.

摘要

目的

本研究旨在探讨内镜下经鼻视神经管减压术(ETOCD)治疗间接性外伤性视神经病变(TON)患者的临床疗效,并确定相关的预后因素。

方法

回顾性分析2017年8月至2019年5月接受ETOCD手术的72例间接性TON患者。采用配对t检验比较ETOCD术前和术后的视力(VA),并采用多元线性回归分析来区分潜在的预后因素。

结果

在分析的患者中,术后VA(-2.87±0.19)显著高于术前VA(-3.92±0.13)(P<0.05)。多元线性回归分析模型显示,初始视力差和手术时间延长是VA预后的独立危险因素(P<0.05),但仅手术时间与视力改善程度(IDVA)显著相关(P<0.05)。视神经管骨折、眼眶骨折以及筛窦和/或蝶窦内出血与IDVA和VA预后无显著相关性(P>0.05)。

结论

ETOCD手术可挽救间接性TON患者的视力损害。初始视力越好,术后最终视力结果越好。此外,手术时间越短,VA预后越好,IDVA越高。

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