Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Brain Research Institute, Zhejiang University, Hangzhou, Zhejiang, China.
Neurosurg Rev. 2021 Feb;44(1):19-27. doi: 10.1007/s10143-019-01208-y. Epub 2019 Nov 22.
Traumatic optic neuropathy (TON) is a serious complication of craniofacial trauma, which damages the optic nerve indirectly and leads to dysfunction of visual acuity. The clinical intervention for a patient with TON includes optic canal decompression (with or without steroids), treatment with corticosteroids alone, or observation only. Currently, there is a controversy among clinicians as to which treatment is optimal. An increasing number of retrospective studies have unveiled that patients could experience significant improvement in visual acuity after optic canal decompression surgery, particularly endoscopic transnasal/transethmosphenoid optic canal decompression (ETOCD), either with or without corticosteroids. In this review, we discuss the evolving perspective on surgical treatment, specifically ETOCD, for the management of patients with TON and focus mainly on the therapeutic efficacy, safety, and resulting prognosis in the clinic.
创伤性视神经病变(TON)是颅面外伤的严重并发症,它通过间接损伤视神经而导致视力功能障碍。TON 患者的临床干预包括视神经管减压(伴或不伴类固醇)、单独使用皮质类固醇治疗或仅观察。目前,临床医生对于哪种治疗方法最佳存在争议。越来越多的回顾性研究表明,患者在接受视神经管减压手术后视力明显改善,尤其是内镜经鼻/经蝶入路视神经管减压术(ETOCD),无论是否使用皮质类固醇。在这篇综述中,我们讨论了手术治疗(特别是 ETOCD)在 TON 患者管理中的不断发展的观点,并主要关注其在临床上的治疗效果、安全性和预后。