Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies, School of Atmospheric Sciences, Sun Yat-sen University, Guangzhou, PR China.
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, PR China.
J Hazard Mater. 2020 Sep 5;396:122520. doi: 10.1016/j.jhazmat.2020.122520. Epub 2020 Mar 12.
In this study, an in vitro method was used to simulate lung fluids [Artificial lysosomal fluid (ALF) and Gamble's solution (GS)] to assess how the bioaccessibility of rare earth elements (REEs) in airborne particulate matter (PM) affects human health. Airborne PM samples (PM and PM) were collected in Daqing in Northeast China. The bioaccessible proportions determined for REEs in PM and PM had high variability, which can be attributable to the heterogenic feature of airborne PM and its components, as well as sampling time. Overall, the bioaccessiblity of the REEs in the airborne PM samples was time-dependent. The bioaccessiblity of the REEs varied in PM with different sizes, and it was an order of magnitude higher in ALF than in GS. During both heavy and light pollution, the bioaccessiblity of the REEs in PM was higher than in PM after 24 h of ALF extraction, whereas bioaccessiblity of the REEs in GS followed the opposite trend. The REEs associated with airborne PM had much greater bioaccessiblity as the exposure time increased. The results of this study emphasize the necessity of conducting bioaccessibility experiments with field samples for the proper evaluation of human health risks.
本研究采用体外方法模拟肺液（人工溶酶体液（ALF）和甘布尔溶液（GS）），评估空气中颗粒物（PM）中稀土元素（REEs）的生物可给性如何影响人类健康。在中国东北的大庆采集了空气颗粒物（PM 和 PM）样本。PM 和 PM 中 REEs 的生物可给比例变化很大，这归因于空气颗粒物及其成分的异质性以及采样时间。总体而言，空气中颗粒物样品中 REEs 的生物可给性是时间依赖性的。不同粒径的空气中颗粒物中 REEs 的生物可给性不同，ALF 中的生物可给性比 GS 中高一个数量级。在重污染和轻污染期间，经过 24 小时的 ALF 提取后，PM 中 REEs 的生物可给性高于 PM，而 GS 中的 REEs 则相反。随着暴露时间的增加，与空气颗粒物相关的 REEs 的生物可给性大大增加。本研究的结果强调了对现场样品进行生物可给性实验以正确评估人类健康风险的必要性。
