Duke University Medical Center, Box 2819, Durham, NC 27710, USA.
Division of Cardiovascular Medicine, Duke University Medical Center, Box 2819, Durham, NC 27710, USA.
Cardiol Clin. 2020 May;38(2):239-242. doi: 10.1016/j.ccl.2020.02.002.
Survivorship into adulthood of patients with congenital heart disease is due to improvements in prenatal detection, novel surgeries, and specialized adult congenital heart disease care. As patients survive further into adulthood, long-term complications of congenital and repaired physiology have been more clearly elucidated. The overall mortality of patients with adult congenital heart disease with heart failure is around 4%. Congenital malformations, palliations, residual defects, and resultant physiology impact the right ventricle. This relationship influences morbidity and mortality. For this discussion, focus on atrial septal defects, Ebstein anomaly, Tetralogy of Fallot, transposition of the great vessels, and single right ventricle physiology.
先天性心脏病患者进入成年后的存活率得益于产前检测、新型手术和专门的成人先天性心脏病治疗的进步。随着患者进一步进入成年期，先天性和修复后生理的长期并发症已得到更明确的阐明。心力衰竭的成人先天性心脏病患者的总体死亡率约为 4%。先天性畸形、姑息治疗、残余缺陷和由此产生的生理会影响右心室。这种关系会影响发病率和死亡率。在本次讨论中，重点关注房间隔缺损、Ebstein 畸形、法洛四联症、大动脉转位和单右心室生理。
