Yamawaki Takemori
Hiroshima City Hiroshima Citizens Hospital.
Brain Nerve. 2020 Apr;72(4):331-343. doi: 10.11477/mf.1416201532.
Differentiating Parkinson's disease (PD) from multiple system atrophy with predominant parkinsonism (MSA-P) or progressive supranuclear palsy-parkinsonism (PSP-P) in early stages of the disease is extremely difficult. MSA-P and PSP-P are often misdiagnosed as PD. MSA-P and PSP-P may be diagnosed in their early stages by considering clinical symptoms and neuroradiological findings together. Diffusion weighted images, T2 weighted images and proton density weighted images are useful for diagnosis MSA-P in early stages , while the magnetic resonance parkinsonism index is useful tool for diagnosis of PSP-P in the early stage.
在帕金森病（PD）的早期阶段，将其与以帕金森综合征为主的多系统萎缩（MSA-P）或进行性核上性麻痹-帕金森综合征（PSP-P）相鉴别极为困难。MSA-P和PSP-P常被误诊为PD。通过综合考虑临床症状和神经放射学检查结果，可在MSA-P和PSP-P的早期阶段做出诊断。弥散加权成像、T2加权成像和质子密度加权成像有助于MSA-P的早期诊断，而磁共振帕金森综合征指数是PSP-P早期诊断的有用工具。
