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系统性创新对移植系统转型的影响。德国肺移植系统的经验教训。一项定性研究。

The impact of systemic innovations for transforming transplant systems. Lessons learned from the German lung transplantation system. A qualitative study.

作者信息

Hauerwaas Antoniya, Weisenfeld Ursula

机构信息

Institute of Management and Organisation, Leuphana University, Lueneburg, Germany.

出版信息

Health Syst (Basingstoke). 2019 May 16;9(1):76-93. doi: 10.1080/20476965.2019.1604086. eCollection 2020.

DOI:10.1080/20476965.2019.1604086
PMID:32284853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7144183/
Abstract

The aim of this paper is to demonstrate the potential of the systemic innovations approach for transforming transplantation systems. It explores potential leverage points for intervening in the LTx-system as well as possible paths of transformation. We present possible transition pathways giving the example of the German Lung transplantation system that teeters on the brink of collapse due to system failures and organ scarcity and illustrate systemic innovations as core mechanisms for systems change in health systems. Desk research and semi-structured experts interviews provided qualitative data for a deductive-inductive coding and a rigorous qualitative content analysis of the data. Depending on the systemic innovations chosen to achieve systems change, transplant systems follow different transformational paths: from a collapse to a leapfrogging towards a non-human transplantation system. Thus, global health areas like transplantation benefit from analysis on systemic innovations as these support researchers, public policy and regulators by developing transformative strategies in healthcare systems.

摘要

本文旨在展示系统性创新方法在变革移植系统方面的潜力。它探索了干预肺移植系统的潜在杠杆点以及可能的变革路径。我们以德国肺移植系统为例,该系统因系统故障和器官短缺而濒临崩溃,展示了可能的转型路径,并阐明系统性创新是卫生系统变革的核心机制。案头研究和半结构化专家访谈为演绎-归纳编码和严格的定性内容分析提供了定性数据。根据为实现系统变革而选择的系统性创新,移植系统遵循不同的转型路径:从崩溃到跨越式发展,迈向非人类移植系统。因此,像移植这样的全球卫生领域受益于对系统性创新的分析,因为这些分析通过制定医疗保健系统中的变革性战略来支持研究人员、公共政策和监管机构。

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本文引用的文献

1
Lung Transplantation in Germany Since the Introduction of the Lung Allocation Score.德国自引入肺分配评分系统以来的肺移植情况。
Dtsch Arztebl Int. 2017 Mar 17;114(11):179-185. doi: 10.3238/arztebl.2017.0179.
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Interspecies Chimerism with Mammalian Pluripotent Stem Cells.哺乳动物多能干细胞的种间嵌合体
Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036.
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OPTN/SRTR 2013 Annual Data Report: lung.OPTN/SRTR 2013 年度数据报告:肺。
Am J Transplant. 2015 Jan;15 Suppl 2:1-28. doi: 10.1111/ajt.13200.
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What's new in clinical solid organ transplantation by 2013.2013年临床实体器官移植领域的新进展。
World J Transplant. 2014 Dec 24;4(4):243-66. doi: 10.5500/wjt.v4.i4.243.
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Increased resource use in lung transplant admissions in the lung allocation score era.在肺分配评分时代,肺移植入院时资源使用增加。
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An international comparison of deceased and living organ donation/transplant rates in opt-in and opt-out systems: a panel study.选择加入和选择退出系统中 deceased 和 living 器官捐赠/移植率的国际比较:一项面板研究。 (注:这里的“deceased”和“living”在医学语境下可理解为“已故的”和“活体的”,但从纯字面看原英文表述不太准确,可能是特定研究中的特定指代表述。)
BMC Med. 2014 Sep 24;12:131. doi: 10.1186/s12916-014-0131-4.
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The application of systems thinking in health: why use systems thinking?系统思维在健康领域的应用:为何要运用系统思维?
Health Res Policy Syst. 2014 Aug 26;12:51. doi: 10.1186/1478-4505-12-51.
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Introduction of the lung allocation score in Germany.德国的肺分配评分介绍。
Am J Transplant. 2014 Jun;14(6):1318-27. doi: 10.1111/ajt.12752.
9
Extended criteria donor lungs and clinical outcome: results of an alternative allocation algorithm.扩大标准供体肺与临床结局:一种替代分配算法的结果
J Heart Lung Transplant. 2013 Nov;32(11):1065-72. doi: 10.1016/j.healun.2013.06.021. Epub 2013 Aug 13.
10
Disparities in lung transplantation.肺移植中的差异。
J Heart Lung Transplant. 2013 Jul;32(7):673-4. doi: 10.1016/j.healun.2013.04.015.