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采用两阶段减容手术成功治疗严重下肢淋巴水肿:病例报告

Severe lower limb lymphoedema successfully treated with a two-stage debulking procedure: a case report.

作者信息

Hague Adam, Bragg Thomas, Thomas Melanie, Pike Cheryl, Morgan Karen, Ghattaura Amar

机构信息

The Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea, UK.

Lymphoedema Network Wales, Cimla Health and Social Care Centre, Neath, UK.

出版信息

Case Reports Plast Surg Hand Surg. 2020 Mar 10;7(1):38-42. doi: 10.1080/23320885.2020.1736943. eCollection 2020.

DOI:10.1080/23320885.2020.1736943
PMID:32284952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7144239/
Abstract

Lymphoedema is a chronic condition that has significant functional and psychosocial morbidity. We report a case of severe lower limb lymphoedema successfully treated with a two-stage debulking procedure, highlighting the significant improvements in function and quality of life this operation can have with the appropriate multidisciplinary support.

摘要

淋巴水肿是一种慢性疾病,具有显著的功能和社会心理发病率。我们报告了一例严重下肢淋巴水肿通过两阶段减容手术成功治疗的病例,强调了在适当的多学科支持下,该手术可对功能和生活质量产生显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/a0a52c16ef43/ICRP_A_1736943_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/b9a07a7e5099/ICRP_A_1736943_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/6559ab4940ea/ICRP_A_1736943_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/29e3c5096914/ICRP_A_1736943_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/a0a52c16ef43/ICRP_A_1736943_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/b9a07a7e5099/ICRP_A_1736943_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/6559ab4940ea/ICRP_A_1736943_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/29e3c5096914/ICRP_A_1736943_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3723/7144239/a0a52c16ef43/ICRP_A_1736943_F0004_C.jpg

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IL-6 regulates adipose deposition and homeostasis in lymphedema.白细胞介素-6 调节淋巴水肿中的脂肪沉积和稳态。
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A prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedema.
100 例连续淋巴静脉旁路手术治疗肢体淋巴水肿的前瞻性分析。
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CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis.CD4(+) 细胞通过调节纤维化和淋巴管生成来响应淋巴液淤积。
PLoS One. 2012;7(11):e49940. doi: 10.1371/journal.pone.0049940. Epub 2012 Nov 20.
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Immunopathogenesis of lymphatic filarial disease.淋巴丝虫病的免疫发病机制。
Semin Immunopathol. 2012 Nov;34(6):847-61. doi: 10.1007/s00281-012-0346-4. Epub 2012 Oct 3.
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Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis.放射治疗通过 TGF-β1 介导的组织纤维化导致皮肤淋巴管丧失和淋巴功能障碍。
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