Yeung K Y, Bonnet J D
Cancer. 1977 May;39(5):2286-9. doi: 10.1002/1097-0142(197705)39:5<2286::aid-cncr2820390549>3.0.co;2-j.
Six months after right-sided spontaneous pneumothorax developed in a 56-year-old man, squamous cell carcinoma was discovered in the ipsilateral lung. Fifteen cases of bronchogenic carcinoma presenting as spontaneous pneumothorax have been reported in the English language literature. Possible pathogenetic mechanisms include: direct tumor invasion of pleura; rupture of a subpleural bleb (in an area of obstructive emphysema) or an emphysematous bulla (in an overexpanded portion of the lung associated with lobar or segmental collapse); or unknown. Patients with spontaneous pneumothorax who fail to achieve complete expansion after three weeks of therapy or who have persistent roentgenographic pulmonary infiltration should undergo further investigation for bronchogenic carcinoma.
一名56岁男性出现右侧自发性气胸6个月后，在同侧肺中发现了鳞状细胞癌。英文文献中已报道了15例表现为自发性气胸的支气管源性癌病例。可能的发病机制包括：肿瘤直接侵犯胸膜；（在阻塞性肺气肿区域）胸膜下肺大疱破裂或（在与肺叶或肺段萎陷相关的肺过度膨胀部分）肺气肿性大疱破裂；或病因不明。治疗三周后未能完全复张或持续存在X线肺部浸润的自发性气胸患者，应进一步检查是否患有支气管源性癌。
