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产科肛门括约肌损伤复发的危险因素和正中旁会阴切开术的作用:国家注册分析。

Risk factors for the recurrence of obstetrical anal sphincter injury and the role of a mediolateral episiotomy: an analysis of a national registry.

机构信息

Department of Obstetrics and Gynaecology, Amphia Hospital Breda, Breda, the Netherlands.

Department of Medical Informatics, Academic Medical Centre, Amsterdam, the Netherlands.

出版信息

BJOG. 2020 Jul;127(8):951-956. doi: 10.1111/1471-0528.16263. Epub 2020 Apr 30.

DOI:10.1111/1471-0528.16263
PMID:32285571
Abstract

OBJECTIVE

The assessment of risk factors, including mediolateral episiotomy (MLE), for the recurrence of obstetric anal sphincter injury (rOASI).

DESIGN

Population-based cohort study.

SETTING

Data from the nationwide database of the Dutch Perinatal Registry (Perined).

POPULATION

A cohort of 391 026 women at term, of whom 9943 had an OASI in their first delivery and had a second vaginal delivery of a liveborn infant in cephalic position.

METHODS

Possible risk factors were tested for statistical significance using univariate and multivariate logistic regression analysis.

MAIN OUTCOME MEASURES

Rate of rOASI.

RESULTS

The rate of rOASI was 5.8%. Multivariate analysis identified a birthweight of ≥4000 g (adjusted OR, aOR, 2.1, 95% CI 1.6-2.6) and a duration of second stage of ≥30 minutes (aOR 1.8, 95% CI 1.4-2.3) as statistically significant risk factors for rOASI. Mediolateral episiotomy was associated with a statistically significant lower rate of rOASI in spontaneous vaginal delivery (SVD) (aOR 0.4, 95% CI 0.3-0.5) and in operative vaginal delivery (OVD) (aOR 0.2, 95% CI 0.1-0.5).

CONCLUSIONS

Women with a history of OASI have a higher rate of OASI in their next delivery. Duration of the second stage of ≥30 minutes and a birthweight of ≥4000 g are significantly associated with an increased rate of rOASI. Mediolateral episiotomy is associated with a significantly lower rate of rOASI in both SVD and OVD.

TWEETABLE ABSTRACT

Mediolateral episiotomy is associated with a significant lower recurrence rate of OASI in women with an OASI in their first delivery.

摘要

目的

评估包括会阴正中切开术(MLE)在内的危险因素对产科肛门括约肌损伤(rOASI)复发的影响。

设计

基于人群的队列研究。

设置

荷兰围产期登记处(Perined)全国数据库的数据。

人群

足月分娩的 391026 名妇女队列,其中 9943 人在首次分娩中发生 OASI,且第二次阴道分娩为头位活产。

方法

使用单变量和多变量逻辑回归分析测试可能的危险因素的统计学意义。

主要观察指标

rOASI 发生率。

结果

rOASI 的发生率为 5.8%。多变量分析确定,出生体重≥4000g(调整后的比值比[aOR],2.1,95%置信区间[CI] 1.6-2.6)和第二产程持续时间≥30 分钟(aOR 1.8,95%CI 1.4-2.3)为 rOASI 的统计学显著危险因素。会阴正中切开术与自然分娩(SVD)(aOR 0.4,95%CI 0.3-0.5)和阴道助产分娩(OVD)(aOR 0.2,95%CI 0.1-0.5)中 rOASI 的发生率统计学显著降低相关。

结论

有 OASI 病史的妇女在下一次分娩中发生 OASI 的比率较高。第二产程持续时间≥30 分钟和出生体重≥4000g 与 rOASI 发生率增加显著相关。会阴正中切开术与 SVD 和 OVD 中 rOASI 的发生率统计学显著降低相关。

推文摘要

在首次分娩中发生 OASI 的妇女中,会阴正中切开术与 OASI 复发率显著降低相关。

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