Fernandez-Gavarron F, Huque T, Rabinowitz J L, Brand J G
Department of Biochemistry, Faculty of Medicine, U.N.A.M. Mexico D.F.
Bone Miner. 1988 Mar;3(4):283-91.
The incorporation of lanthanum in the form of 140-lanthanum onto the surface of teeth, bone and synthetic hydroxyapatite was investigated. A small amount of lanthanum was taken up by the surface of all of the materials studied regardless of their origin. The depth of penetration into bone and teeth was dependent upon lanthanum concentration and time of incubation and, in these experiments, ranged from an estimated 5 to 15 microns. An exchange of lanthanum for calcium in the apatite matrix may be responsible for increased resistance of the hard tissues to acid dissolution. The effects of pH, temperature, time and concentration of the lanthanum solutions on this incorporation were investigated. Possible clinical uses of this effect are discussed.
研究了以¹⁴⁰ - 镧的形式将镧掺入牙齿、骨骼和合成羟基磷灰石表面的情况。无论所研究材料的来源如何，所有材料的表面都吸收了少量的镧。镧渗入骨骼和牙齿的深度取决于镧的浓度和孵育时间，在这些实验中，深度估计在5至15微米之间。磷灰石基质中镧与钙的交换可能是硬组织对酸溶解抵抗力增强的原因。研究了镧溶液的pH值、温度、时间和浓度对这种掺入的影响。讨论了这种效应可能的临床用途。
