Wolkowicz J, Burgess J H
Division of Cardiology, Montreal General Hospital, Quebec.
Can J Cardiol. 1988 Oct;4(7):352-4.
An Inuit family from Cape Dorset, Northwest Territories is described; six had documented complete heart block, one high grade atrioventricular block, one bi- or trifascicular block and all suffered syncope. One other member received a pacemaker for unknown reasons. Two of three middle-aged relatives had minor conduction abnormalities. All younger family members who were examined had no conduction problems. This suggests a heritable form of adult onset complete heart block, the largest series reported in the English literature.
本文描述了一个来自西北地区多尔塞特角的因纽特人家庭;其中六人被记录有完全性心脏传导阻滞,一人为高度房室传导阻滞,一人为双束支或三束支传导阻滞,所有人均有晕厥症状。另一名家庭成员不明原因地接受了起搏器植入。三名中年亲属中有两人有轻度传导异常。所有接受检查的年轻家庭成员均无传导问题。这表明存在一种成人起病的遗传性完全性心脏传导阻滞,这是英文文献中报道的最大系列病例。