Elshamly Mousa, Nour Mohamed O, Omar Abdelmaaboud M M
Department of Chest Diseases, Faculty of Medicine, Al-Azhar University, Egypt.
Department of Community & Occupational Medicine, Faculty of Medicine, Al-Azhar University (Damietta Branch), Egypt.
Egypt J Chest Dis Tuberc. 2016 Oct;65(4):831-839. doi: 10.1016/j.ejcdt.2016.06.002. Epub 2016 Jun 18.
Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20-50%.
To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).
54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.
The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was , Influenza H1N1, and . Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.
SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is , Influenza H1N1 and . SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.
重症社区获得性肺炎（SCAP）是一种常见且可能危及生命的疾病。所有住院的社区获得性肺炎（CAP）患者中约10%需要入住重症监护病房（ICU），这些患者的死亡率达20% - 50%。
评估重症社区获得性肺炎（SCAP）的临床表现、细菌学特征及预后。
2015年8月至2016年3月期间，入住爱资哈尔大学胡笙医院呼吸科、有重症社区获得性肺炎症状和体征的54例患者接受了全面临床检查、胸部X线检查、全血细胞计数、痰及血培养、针对疑似甲型H1N1流感和中东呼吸综合征冠状病毒病例的聚合酶链反应（PCR）检测、治疗、随访、数据收集及统计分析。
本研究纳入了54例入住爱资哈尔大学胡笙医院呼吸科的重症社区获得性肺炎患者，其中男性26例，女性28例。最常见的合并症是糖尿病和高血压。最常见的表现是发热、咳嗽、呼吸困难和低氧血症。2例患者出现肾衰竭，4例患者发生感染性休克。最常见的分离出的病原体是甲型H1N1流感病毒等。死亡率为24%，合并症患者的死亡率高于无合并症患者。
SCAP在合并症患者中更常见。SCAP最常见的分离致病病原体是甲型H1N1流感病毒等。SCAP与显著的死亡率相关，早期识别和及时治疗可能改善预后。
