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伊拉克巴士拉人群线粒体 DNA(高变区 I)多样性。

Mitochondrial DNA (hypervariable region I) diversity in Basrah population - Iraq.

机构信息

Biology Department, College of Science, University of Basrah, Iraq.

Biology Department, College of Science, University of Basrah, Iraq.

出版信息

Genomics. 2020 Sep;112(5):3560-3564. doi: 10.1016/j.ygeno.2020.04.004. Epub 2020 Apr 11.

Abstract

In attempt to investigate the origin of Basrah, we examined the mitochondrial DNA(mt-DNA) variations by hypervariable segment 1(HVS1) Sequencing and determination of specific site haplogroups. In Basrah, no significant differences diversity among Iraqis' HVS1 compared with other countries. The values were within the range of gene diversity across the Middle East and exhibited the unimodal pattern of differences in the pairwise sequence. Given the small genetic differences between people living in this area, phylogenetic analysis showed a large variability of the communities of Basrah; they didn't cluster on the phylogenetic tree.

摘要

为了探究巴士拉的起源,我们通过高变区 1(HVS1)测序和特定位点单倍群的确定来研究线粒体 DNA(mt-DNA)的变异。在巴士拉,与其他国家相比,伊拉克人 HVS1 的多样性没有显著差异。这些数值在整个中东的基因多样性范围内,并且在成对序列的差异上表现出单峰模式。鉴于生活在该地区的人们之间的遗传差异较小,系统发生分析显示巴士拉社区的多样性很大;它们没有在系统树上聚类。

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