Schuettfort Victor, Shariat Shahrokh F, Rink Michael
Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Urologie, Hamburg.
Allgemeines Krankenhaus der Stadt Wien-Klinikum der Medizinischen Universität Wien, Univ. Klinik für Urologie, Wien.
Aktuelle Urol. 2020 Aug;51(4):353-362. doi: 10.1055/a-1146-2938. Epub 2020 Apr 14.
Radical cystectomy is the gold standard in treatment of muscle invasive bladder carcinoma. Especially for patients with advanced tumours, multimodal therapies play an important role in optimising patient care. In older patients with multiple comorbidities, who are not eligible for surgery, alternative treatment modalities are needed as well. This article summarises the current literature on multimodal treatment options in a neoadjuvant and adjuvant setting and analyses alternative potentially curative treatments. The article also summarises the initial results using checkpoint inhibitors in a multimodal treatment setting.
根治性膀胱切除术是治疗肌层浸润性膀胱癌的金标准。特别是对于晚期肿瘤患者,多模式治疗在优化患者护理方面发挥着重要作用。对于有多种合并症且不适合手术的老年患者,也需要其他治疗方式。本文总结了新辅助和辅助治疗环境下多模式治疗方案的当前文献,并分析了其他潜在的根治性治疗方法。本文还总结了在多模式治疗环境中使用检查点抑制剂的初步结果。