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类风湿关节炎患者中金盐和非甾体抗炎药所致肾损伤的评估。

Evaluation of the renal injury from gold salts and nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis.

作者信息

Giordano N, Frati E, Fioravanti A, Taddeo A, Morozzi G, Marcolongo R

机构信息

Institute of Rheumatology, University of Siena, Italy.

出版信息

Clin Rheumatol. 1988 Sep;7(3):342-6. doi: 10.1007/BF02239190.

DOI:10.1007/BF02239190
PMID:3229079
Abstract

The urinary excretion of proteins, N-acetyl-3-glucosaminidase and leucine aminopeptidase, was measured in 50 patients with rheumatoid arthritis (RA), of whom 20 subjects were on nonsteroidal anti-inflammatory drugs (NSAIDs) and 30 on gold salts. No pathological changes of the above-mentioned urinary parameters have been observed in the group of RA patients, in comparison with control subjects and patients suffering from osteoarthritis treated with NSAIDs.

摘要

对50例类风湿关节炎(RA)患者的蛋白质、N-乙酰-3-葡萄糖苷酶和亮氨酸氨肽酶的尿排泄量进行了测定,其中20例患者服用非甾体抗炎药(NSAIDs),30例服用金盐。与对照组以及接受NSAIDs治疗的骨关节炎患者相比,RA患者组未观察到上述尿液参数的病理变化。

相似文献

1
Evaluation of the renal injury from gold salts and nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis.类风湿关节炎患者中金盐和非甾体抗炎药所致肾损伤的评估。
Clin Rheumatol. 1988 Sep;7(3):342-6. doi: 10.1007/BF02239190.
2
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本文引用的文献

1
Gold Therapy in Rheumatoid Arthritis: Final Report of a Multicentre Controlled Trial.类风湿关节炎的金疗法:一项多中心对照试验的最终报告。
Ann Rheum Dis. 1961 Dec;20(4):315-34. doi: 10.1136/ard.20.4.315.
2
THE KIDNEY FUNCTION IN RELATION TO DRUG CONSUMPTION IN PATIENTS WITH RHEUMATOID ARTHRITIS. (V).类风湿关节炎患者的肾功能与药物消费的关系。(五)
Acta Rheumatol Scand. 1963;9:122-40. doi: 10.3109/rhe1.1963.9.issue-1-4.17.
3
Acute interstitial nephritis due to drugs: Review of the literature with a report of nine cases.药物所致急性间质性肾炎:文献复习并附9例报告
Ann Intern Med. 1980 Nov;93(5):735-41. doi: 10.7326/0003-4819-93-5-735.
4
Reversible acute renal insufficiency and hyperkalemia following indomethacin therapy.吲哚美辛治疗后出现的可逆性急性肾功能不全和高钾血症。
JAMA. 1981 Jul 10;246(2):154-5.
5
Renal effects of drugs that inhibit prostaglandin synthesis.抑制前列腺素合成药物的肾脏效应
Kidney Int. 1980 Nov;18(5):609-22. doi: 10.1038/ki.1980.179.
6
Renal injury in patients with rheumatoid arthritis treated with gold.接受金制剂治疗的类风湿关节炎患者的肾损伤
Clin Pharmacol Ther. 1980 Aug;28(2):216-22. doi: 10.1038/clpt.1980.153.
7
Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs.非甾体抗炎药所致肾功能不全风险的识别
Arch Intern Med. 1983 Jun;143(6):1130-4.
8
Nephrotoxicity of nonsteroidal anti-inflammatory agents.非甾体抗炎药的肾毒性
Am J Kidney Dis. 1983 Jan;2(4):478-84. doi: 10.1016/s0272-6386(83)80083-3.
9
Comparative pharmacokinetics of parenteral and oral gold compounds.肠胃外和口服金化合物的比较药代动力学
J Rheumatol Suppl. 1982 Jul-Aug;8:99-109.
10
Nonsteroidal anti-inflammatory drugs and renal disease.非甾体抗炎药与肾脏疾病
JAMA. 1984 Mar 9;251(10):1299-300.