类风湿关节炎患者中金盐和非甾体抗炎药所致肾损伤的评估。
Evaluation of the renal injury from gold salts and nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis.
作者信息
Giordano N, Frati E, Fioravanti A, Taddeo A, Morozzi G, Marcolongo R
机构信息
Institute of Rheumatology, University of Siena, Italy.
出版信息
Clin Rheumatol. 1988 Sep;7(3):342-6. doi: 10.1007/BF02239190.
The urinary excretion of proteins, N-acetyl-3-glucosaminidase and leucine aminopeptidase, was measured in 50 patients with rheumatoid arthritis (RA), of whom 20 subjects were on nonsteroidal anti-inflammatory drugs (NSAIDs) and 30 on gold salts. No pathological changes of the above-mentioned urinary parameters have been observed in the group of RA patients, in comparison with control subjects and patients suffering from osteoarthritis treated with NSAIDs.
对50例类风湿关节炎（RA）患者的蛋白质、N-乙酰-3-葡萄糖苷酶和亮氨酸氨肽酶的尿排泄量进行了测定，其中20例患者服用非甾体抗炎药（NSAIDs），30例服用金盐。与对照组以及接受NSAIDs治疗的骨关节炎患者相比，RA患者组未观察到上述尿液参数的病理变化。
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