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儿童脊柱硬膜外脓肿:基于病例的综述

Spinal epidural abscess in children: a case-based review.

作者信息

Spennato Pietro, Renedo Daniela, Cascone Daniele, Mirone Giuseppe, Imperato Alessia, Di Martino Giuliana, Cinalli Giuseppe

机构信息

Department of Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Department of Neurosurgery, University of Buenos Aires School of Medicine, Buenos Aires, Argentina.

出版信息

Childs Nerv Syst. 2020 Jul;36(7):1385-1392. doi: 10.1007/s00381-020-04609-3. Epub 2020 Apr 14.

Abstract

BACKGROUND

Pediatric spinal epidural abscess is a major suppurative infection of the central nervous system. It is an extremely rare pathology carrying serious risk of permanent neurological sequelae if is not properly treated.

METHODS AND RESULTS

All the pertinent literature was analyzed, focused on pediatric cases of spinal epidural abscess and its peculiar features. Two illustrative cases are also presented. The first case is that of a 9-year old girl who took medical attention, when she was already paraplegic. Despite prompt surgical evacuation and good neuroradiological outcome and intensive rehabilitation, motor deficits did not recover after surgery. The second case was that of a 14-year old girl who presented with fever, neck pain, and torticollis. Prompt diagnosis, decompressive surgery, and 6 weeks of antibiotics allowed good neurological outcome.

CONCLUSIONS

The management of spinal epidural abscess includes evacuation of the abscess with decompression of the spinal cord and prolonged antibiotic treatment. The presence of neurological deficit and the delay in the initiation of proper treatment are the two factors that more worsen prognosis.

摘要

背景

小儿脊柱硬膜外脓肿是中枢神经系统的一种主要化脓性感染。它是一种极其罕见的病理情况,如果治疗不当,会带来永久性神经后遗症的严重风险。

方法与结果

对所有相关文献进行了分析,重点关注小儿脊柱硬膜外脓肿病例及其独特特征。还介绍了两个典型病例。第一个病例是一名9岁女孩,就医时已出现截瘫。尽管及时进行了手术引流,神经放射学结果良好且进行了强化康复治疗,但术后运动功能障碍并未恢复。第二个病例是一名14岁女孩,表现为发热、颈部疼痛和斜颈。及时诊断、减压手术以及6周的抗生素治疗使神经功能恢复良好。

结论

脊柱硬膜外脓肿的治疗包括脓肿引流、脊髓减压以及延长抗生素治疗。神经功能缺损的存在和开始适当治疗的延迟是两个使预后更恶化的因素。

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