Rizkaprilisa Windy, Marsono Yustinus, Indrati Retno
Department of Food and Agricultural Product Technology, Faculty of Agriculturural Technology, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
Prev Nutr Food Sci. 2020 Mar 31;25(1):93-97. doi: 10.3746/pnf.2020.25.1.93.
(L) DC tempe is a food that functions as an inhibitor of the angiotensin-I-converting enzyme (ACE). The purpose of this research was to study the activity of tempe peptides during the digestive process with pepsin-pancreatin, and absorption of peptides in the small intestine using the inverted intestinal sac method. Our results show that had the highest ACE-inhibiting activity after digestion after fermentation for 72 h (F72). F72 peptide absorption (%) and ACE-inhibitory activity of the absorbed peptides did not significantly differ between the different segments of the small intestine (duodenum, jejunum, and ileum). These results demonstrate that F72 tempe maintains ACE-inhibitory activity in each segment of the small intestine after both digestion and absorption.
豆豉是一种可作为血管紧张素转换酶（ACE）抑制剂的食物。本研究的目的是利用胃蛋白酶 - 胰酶研究豆豉肽在消化过程中的活性，并采用翻转肠囊法研究肽在小肠中的吸收情况。我们的结果表明，发酵72小时（F72）后的豆豉在消化后具有最高的ACE抑制活性。F72肽的吸收百分比以及吸收肽的ACE抑制活性在小肠的不同节段（十二指肠、空肠和回肠）之间没有显著差异。这些结果表明，F72豆豉在消化和吸收后在小肠的每个节段中都保持ACE抑制活性。
