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应对羟氯喹用于治疗新冠病毒病潜在的全球紧急药品供应挑战。

Meeting the potential emergency global drug supply challenge of hydroxychloroquine for COVID-19.

作者信息

Zhang Tony Y, Zhong Boyu

机构信息

Tyligand Bioscience Ltd. 3728 Jinke Road, Building 1, Zhangjiang Hitech Park, Shanghai, China.

出版信息

Med Drug Discov. 2020 Mar;5:100036. doi: 10.1016/j.medidd.2020.100036. Epub 2020 Apr 9.

Abstract

This paper provides an overview of the current global market and manufacturing landscape for hydroxychloroquine (HCQ). The capacity and capabilities of global producers to meet the potential demand for treating patients inflicted with COVID-19 by the novel corona virus SARS-CoV-2, should HCQ's efficacy be established by more definitive clinical trials, is also assessed. Given the large existing manufacturing base and abundance of raw materials for HCQ, the supply challenge can be met with considerable efforts and international cooperation. Preemptive and coordinated emergency efforts among global governments, regulatory agencies, chemical and pharmaceutical industries are imperative for meeting the potential surge in demand.

摘要

本文概述了当前羟氯喹(HCQ)的全球市场及生产格局。还评估了若羟氯喹的疗效能通过更具权威性的临床试验得以证实,全球生产商满足新型冠状病毒SARS-CoV-2感染患者潜在治疗需求的产能和能力。鉴于羟氯喹现有庞大的生产基础和丰富的原材料,通过相当大的努力和国际合作可以应对供应挑战。全球各国政府、监管机构、化工和制药行业之间开展先发制人的协调应急行动对于应对潜在的需求激增至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af9/7144509/0733ae82c48e/gr1.jpg

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