Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China.
Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Chem Commun (Camb). 2020 May 19;56(40):5441-5444. doi: 10.1039/d0cc01025a.
A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.
基于 DNA 适体的液晶生物传感器用于灵敏检测帕金森病（PD）相关的α-突触核蛋白，已被开发出来。该 LC 生物传感器采用简单且无需标记的方法构建，不仅可以实现早期 PD 诊断，而且还为基于 DNA 适体的检测提供了通用平台。
