Li Z T, Wang X N, Liu X L, Ke J Z, Ruan X N, Qiu H, Yu S Y, Wu K, Yang Y
Shanghai Pudong New Area Center for Disease Control and Prevention, Fudan University Pudong Institute of Preventive Medicine, Shanghai 200136, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Mar 10;41(3):326-330. doi: 10.3760/cma.j.issn.0254-6450.2020.03.009.
To analyze the relationship of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) with diabetes mellitus in community residents aged ≥15 years in Pudong new district of Shanghai, and provide evidence for the prevention and treatment of diabetes mellitus. Using multi-stage stratified cluster sampling method, a total of 7 194 community residents aged ≥15 years were surveyed by using questionnaire, physical examination and laboratory tests in 2016. The relationship of BMI, waist circumference and waist-hip ratio with diabetes mellitus was analyzed by (2) test, single factor linear correlation and logistic regression analyses. In 2016, the crude prevalence rate of diabetes mellitus in Pudong was 27.37, which was 12.75 after standardization. The prevalence rate of diabetes mellitus was slightly higher in men than in women and was increased with age. The levels of FPG, 2 h plasma glucose and HbA1c were positively correlated with BMI, WC and WHR. After adjusting the confounding factors, multiple logistic regression analysis showed that obesity (=1.351, <0.01), excessive waist circumference (=1.255, <0.01) and high WHR (=1.291, <0.01) were risk factors for diabetes mellitus. The increase of obesity, WC and WHR will increase the risk for diabetes mellitus. It is important to maintain healthy weight, especially the control of WC and WHR, reduce the accumulation of abdominal fat to reduce the risk for diabetes mellitus.
分析上海市浦东新区≥15岁社区居民体重指数(BMI)、腰围(WC)、腰臀比(WHR)与糖尿病的关系,为糖尿病防治提供依据。采用多阶段分层整群抽样方法,于2016年对7194名≥15岁社区居民进行问卷调查、体格检查及实验室检测。采用χ²检验、单因素线性相关分析及logistic回归分析BMI、腰围及腰臀比与糖尿病的关系。2016年浦东新区糖尿病粗患病率为27.37%,标化后为12.75%。糖尿病患病率男性略高于女性,且随年龄增加而升高。空腹血糖(FPG)、餐后2小时血糖及糖化血红蛋白(HbA1c)水平与BMI、WC及WHR呈正相关。校正混杂因素后,多因素logistic回归分析显示肥胖(OR =1.351,P<0.01)、腰围超标(OR =1.255,P<0.01)及腰臀比升高(OR =1.291,P<0.01)是糖尿病的危险因素。肥胖、WC及WHR增加会增加患糖尿病风险。维持健康体重,尤其是控制WC及WHR,减少腹部脂肪堆积对降低糖尿病风险具有重要意义。