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[实验性交感神经切除术后肢体不同组织的血液供应与氧平衡]

[The blood supply and oxygen balance of the different tissues of the extremities following experimental sympathectomy].

作者信息

Prokhorov G G

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Oct;74(10):1447-53.

PMID:3229524
Abstract

The experiments in dogs suggested an essential difference in terms of the rearrangement of regional blood circulation in the skin and muscles of the extremity after experimental sympathectomy. Ganglionectomy induced a reduction of general peripheral arterial resistance on the operated side, an increase in the skin tissue blood flow and its oxygenation rate, a deceleration of the process of biological oxidation reducing the capability of muscles to use blood oxygen and cutting down the maximum of oxidase cytochrome (a3) activity. There was no essential change in the regional acid-alkaline balance. The above changes were due to a disturbance of the neurotrophic sympathetic effect on tissues.

摘要

对狗进行的实验表明,实验性交感神经切除术后,肢体皮肤和肌肉局部血液循环的重新分布存在本质差异。神经节切除术导致手术侧总外周动脉阻力降低,皮肤组织血流量及其氧合率增加,生物氧化过程减慢,肌肉利用血氧的能力降低,氧化酶细胞色素(a3)活性最大值降低。局部酸碱平衡没有本质变化。上述变化是由于交感神经对组织的营养作用受到干扰所致。

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