Mobasseri Majid, Shirmohammadi Masoud, Amiri Tarlan, Vahed Nafiseh, Hosseini Fard Hossein, Ghojazadeh Morteza
Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Health Promot Perspect. 2020 Mar 30;10(2):98-115. doi: 10.34172/hpp.2020.18. eCollection 2020.
Diabetes is referred to a group of diseases characterized by high glucose levels in blood. It is caused by a deficiency in the production or function of insulin or both, which can occur because of different reasons, resulting in protein and lipid metabolic disorders. The aim of this study was to systematically review the prevalence and incidence of type 1 diabetes in the world. A systematic search of resources was conducted to investigate the prevalence and incidence of type 1 diabetes in the world. The databases of Medline (via PubMed and Ovid),ProQuest, Scopus, and Web of Science from January 1980 to September 2019 were searched to locate English articles. The located articles were screened in multiple levels of title, abstract,and full-text and final studies that met the inclusion criteria were retrieved and included in the study. From 1202 located articles, 193 studies were included in this systematic review. The results of meta-analysis showed that the incidence of type 1 diabetes was 15 per 100,000 people and the prevalence was 9.5% (95% CI: 0.07 to 0.12) in the world, which was statistically significant. According to the results, the incidence and prevalence of type 1 diabetes are increasing in the world. As a result, insulin will be difficult to access and afford, especially in underdeveloped and developing countries.
糖尿病是指一组以血液中葡萄糖水平升高为特征的疾病。它是由胰岛素分泌不足或功能缺陷或两者兼而有之引起的，这可能由于不同原因而发生，导致蛋白质和脂质代谢紊乱。本研究的目的是系统评价全球1型糖尿病的患病率和发病率。我们对相关资源进行了系统检索，以调查全球1型糖尿病的患病率和发病率。检索了1980年1月至2019年9月期间Medline（通过PubMed和Ovid）、ProQuest、Scopus和Web of Science数据库中的英文文章。对检索到的文章进行了标题、摘要和全文的多层次筛选，最终检索并纳入了符合纳入标准的研究。从1202篇检索到的文章中，193项研究被纳入本系统评价。荟萃分析结果显示，全球1型糖尿病的发病率为每10万人中有15例，患病率为9.5%（95%CI：0.07至0.12），具有统计学意义。根据研究结果，全球1型糖尿病的发病率和患病率正在上升。因此，胰岛素将难以获得和负担得起，尤其是在欠发达国家和发展中国家。
