Centre for Materials Science, School of Chemistry and Physics, Institute for Future Environments, Queensland University of Technology (QUT), 2 George Street, QLD 4000, Brisbane, Australia.
Chem Commun (Camb). 2020 May 7;56(37):4986-4989. doi: 10.1039/d0cc01557a. Epub 2020 Apr 16.
Herein, we introduce a fast, additive-free, ambient temperature photochemical approach - utilising the novel Diels-Alder cycloaddition of a photo-active ortho-methylbenzaldehyde (oMBA) with a terminal alkyne - for preparing functional acid-sensitive profluorescent nano-/microspheres in one step. Not previously reported, the possibility of applying such a reaction in the context of particle synthesis provides new possibilities for particle design, where multi-step reactivity can be gated into distinct steps. First, a photochemically-gated particle formation step yields a material possessing a reactive, spring-loaded intermediate at every cross-linking point. A second, on-demand step to initiate fluorescence generation subsequently imparts the properties of the chemical transformation to the material itself. The synthesised particles are narrow-disperse with an average diameter ranging from 170-380 nm.
在此，我们介绍了一种快速、无添加剂、环境温度的光化学方法 - 利用新型光活性邻甲基苯甲醛（oMBA）与末端炔烃的 Diels-Alder 环加成反应 - 一步制备功能性酸敏感的荧光纳米/微球。以前从未报道过，在颗粒合成的背景下应用这种反应为颗粒设计提供了新的可能性，其中多步反应可以被分为不同的步骤。首先，光化学门控的颗粒形成步骤产生了一种在每个交联点都具有反应性、弹簧加载的中间产物的材料。随后的按需引发荧光生成的第二步反应赋予材料自身化学转化的特性。所合成的颗粒具有窄分散性，平均直径范围为 170-380nm。
