Department of Dermatology, Nippon Medical School, Tokyo, Japan.
Department of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Australas J Dermatol. 2020 Aug;61(3):e333-e338. doi: 10.1111/ajd.13283. Epub 2020 Apr 16.
Chronic spontaneous urticaria (CSU) is defined as the spontaneously appearing weals and/or angioedema for more than 6 weeks. Dietary habits can modulate the pathogenesis of CSU. However, dietary intakes of nutrients or food in CSU patients, compared with healthy controls, have not been examined in quality and quantity.
We evaluated dietary habits in adult Japanese patients with chronic spontaneous urticaria using a validated, brief-type self-administered diet history questionnaire and compared the results to those of age- and sex-matched healthy controls. The severity of CSU was evaluated using the Urticaria Control Test.
Japanese CSU patients showed higher body mass indices, higher intakes of eggs, vegetables other than green/yellow vegetables/mushrooms/algae, cholesterol, folic acid, dietary fibres, vitamin D, vitamin K, Cu, Fe, Pi, Ca, Mg, Na and salt, and lower intake of alcohol, compared to controls. The logistic regression analysis showed that CSU was associated with high body mass index and high intake of eggs. The intake of beverages was higher in uncontrolled CSU patients (Urticaria Control Test ≦11 points) than in controlled patients. The logistic regression analysis showed that uncontrolled CSU was associated with high intake of beverages. The intake of coffee, caffeine-rich and non-alcohol beverage, in uncontrolled CSU patients was higher than that in controlled patients.
Chronic spontaneous urticaria was associated with high body mass index and high intake of eggs. Uncontrolled CSU was associated with high intake of beverages. Further studies should elucidate the relationships of these results with the development or exacerbation of CSU.
慢性自发性荨麻疹（CSU）定义为自发出现的风团和/或血管性水肿超过 6 周。饮食习惯可以调节 CSU 的发病机制。然而，与健康对照组相比，CSU 患者的营养素或食物摄入情况在质量和数量上尚未得到检查。
我们使用经过验证的简短型自我管理饮食史问卷评估了成年日本 CSU 患者的饮食习惯，并将结果与年龄和性别匹配的健康对照组进行了比较。CSU 的严重程度使用荨麻疹控制测试进行评估。
与对照组相比，日本 CSU 患者的体重指数更高，鸡蛋、除绿叶蔬菜/黄色蔬菜/蘑菇/藻类以外的蔬菜、胆固醇、叶酸、膳食纤维、维生素 D、维生素 K、Cu、Fe、Pi、Ca、Mg、Na 和盐的摄入量更高，而酒精摄入量则更低。逻辑回归分析表明，CSU 与高体重指数和高鸡蛋摄入量有关。未控制的 CSU 患者（荨麻疹控制测试≦11 分）的饮料摄入量高于控制患者。逻辑回归分析表明，未控制的 CSU 与饮料摄入量高有关。未控制的 CSU 患者饮用的咖啡、含咖啡因的非酒精饮料的摄入量高于控制患者。
慢性自发性荨麻疹与高体重指数和高鸡蛋摄入量有关。未控制的 CSU 与饮料摄入量高有关。进一步的研究应阐明这些结果与 CSU 的发展或恶化之间的关系。
