Heart Institute (Incor), University of Sao Paulo Medical School, Sao Paulo, Brazil.
Hospital das Clinicas and Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
J Cardiovasc Electrophysiol. 2020 Jun;31(6):1413-1419. doi: 10.1111/jce.14499. Epub 2020 Apr 22.
Catheter ablation of the parahisian accessory pathways (PHAP) has been established as the definitive therapy for this type of arrhythmia. However, the PHAP proximity to the normal atrioventricular conduction system makes the procedure technically challenging. Here, we have reported a case series of 20 patients with PHAP who underwent aortic access ablation to evaluate the safety and efficacy of this approach in the PHAP ablation.
The ablation through the aortic cusps was the successful approach in 13 of 20 (65%) of the cases. In 11 patients, the aortic approach was the initial strategy for ablation, and the accessory pathway was eliminated in seven (63.6%) of them. The aortic approach followed a failed right-sided attempt in nine patients. In six (66.7%) patients, the ablation was successful with the aortic approach. The only independent predictor for the successful ablation with each approach was the earliest ventricular activation before delta wave (predelta time) and a right-sided earliest ventricular activation of more than 23 ms had high sensitivity and specificity for right-sided success. Systematically using the two strategies (right and left approaches), the ablation of the PHAP was successful in 18 (90%) patients.
The aortic approach seems to be a safe and effective strategy for the ablation of PHAP. It can be used when the right-sided approach fails or even considered as an initial strategy when the predelta time is less than 23 ms in the right septal region. When combining the right- and left-sided approaches, the success rate is high. We believe that the retrograde aortic approach remains a key tool for this challenging ablation.
经导管消融心房间旁路(PHAP)已被确立为治疗此类心律失常的首选方法。然而,PHAP 与正常房室传导系统的接近使得该手术在技术上具有挑战性。在这里,我们报告了 20 例 PHAP 患者的病例系列,他们接受了主动脉瓣口消融,以评估该方法在 PHAP 消融中的安全性和疗效。
在 20 例患者中,有 13 例(65%)通过主动脉瓣口消融成功。在 11 例患者中,主动脉瓣口消融是初始消融策略,其中 7 例(63.6%)患者旁路被消除。主动脉瓣口消融是在 9 例患者右侧尝试失败后进行的。在 6 例(66.7%)患者中,主动脉瓣口消融成功。每种方法消融成功的唯一独立预测因素是 delta 波前最早心室激活(预 delta 时间),而右室最早心室激活超过 23ms 对右室成功具有高灵敏度和特异性。系统地使用两种策略(右侧和左侧),18 例(90%)PHAP 消融成功。
主动脉瓣口途径似乎是消融 PHAP 的一种安全有效的策略。当右侧方法失败时,可以使用该方法,甚至当右侧间隔区预 delta 时间小于 23ms 时,可以考虑作为初始策略。当结合右侧和左侧方法时,成功率较高。我们认为逆行主动脉瓣口途径仍然是这种具有挑战性的消融的关键工具。