Department of Oncology, Minimally Invasive Urology and Andrology, Careggi Hospital, University of Florence, Florence, Italy -
Department of Oncology, Minimally Invasive Urology and Andrology, Careggi Hospital, University of Florence, Florence, Italy.
Minerva Urol Nefrol. 2020 Dec;72(6):691-697. doi: 10.23736/S0393-2249.20.03792-3. Epub 2020 Apr 16.
Chronic obstruction and stones formation are common in pelvic ectopic kidney (PEK), and stone treatment in such conditions can be challenging. Aim of this systematic review was to examine all the available active treatment modalities for PEK stones in order to critically appraise their advantages and limitations.
A search on Medline, Embase, and the Cochrane Library databases was performed to identify literature focused on the active treatment of PEK stones. Original articles, case report and case series were included in the search. The systematic review was conducted in accordance to the PRISMA checklist. The study period went from inception of databases to October 2019.
Of the 256 articles identified, 23 met the inclusion criteria. 334 patients were included in the studies and 119 had stones in PEK. Five patients were treated with SWL, 40 with ureterorenoscopy, 37 with percutaneous nephrolithotomy both by ultrasound/X-Ray or lap-assisted puncture, and 37 with minimally invasive laparoscopic or robot assisted pyelolithotomy. Overall, stone free rate after first treatment was higher in minimally invasive laparoscopic or robot assisted pyelolithotomy (97.2%) compared to percutaneous nephrolithotomy (84.96%) and ureterorenoscopy studies (65.94%). The higher complication rate was reported in percutaneous nephrolithotomy not lap-assisted (33.3%).
The choice of the approach depends on different factors such as stone size, density and location in accordance with upper urinary tract alterations, kidney anatomy and operator experience. The choice of a retrograde, percutaneous or lap/robot approach should be carefully selected evaluating upper urinary tract anatomy and stone features.
慢性梗阻和结石形成是盆腔异位肾(PEK)的常见并发症,此类情况下的结石治疗具有挑战性。本系统评价的目的是研究所有可用于治疗 PEK 结石的积极治疗方法,以批判性地评估其优缺点。
对 Medline、Embase 和 Cochrane Library 数据库进行了检索,以确定侧重于 PEK 结石积极治疗的文献。原始文章、病例报告和病例系列均包含在搜索范围内。系统评价是按照 PRISMA 清单进行的。研究期间为数据库建立至 2019 年 10 月。
在确定的 256 篇文章中,有 23 篇符合纳入标准。研究共纳入 334 例患者,其中 119 例患者的肾结石位于 PEK。5 例患者接受了体外冲击波碎石术(SWL)治疗,40 例患者接受了输尿管镜碎石术治疗,37 例患者接受了经皮肾镜碎石术治疗(超声/X 射线或腹腔镜辅助穿刺),37 例患者接受了微创腹腔镜或机器人辅助肾盂切开取石术治疗。总的来说,微创腹腔镜或机器人辅助肾盂切开取石术的首次治疗后结石清除率(97.2%)高于经皮肾镜碎石术(84.96%)和输尿管镜碎石术(65.94%)。未采用腹腔镜辅助的经皮肾镜碎石术的并发症发生率较高(33.3%)。
治疗方法的选择取决于多种因素,如结石大小、密度以及与上尿路改变、肾脏解剖结构和术者经验相关的位置。应根据上尿路解剖结构和结石特征仔细选择逆行、经皮或腹腔镜/机器人方法。