Manoach M, Varon D, Neuman M, Erez M
Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Int J Cardiol. 1988 Dec;21(3):211-7. doi: 10.1016/0167-5273(88)90099-x.
Ventricular antiarrhythmic therapy is aimed traditionally at preventing arrhythmias and ventricular fibrillation. Recently, a new approach has been introduced, where drug therapy facilitates the ability of the heart for spontaneous defibrillation. The chemical features and the electrophysiologic properties are discussed below. The introduction of this new group of defibrillating antiarrhythmic drugs implies the extension of the common classification of antiarrhythmic drugs.
传统上,心室抗心律失常治疗旨在预防心律失常和心室颤动。最近,引入了一种新方法,即药物治疗可促进心脏自发除颤的能力。以下将讨论其化学特性和电生理特性。这类新型除颤抗心律失常药物的引入意味着抗心律失常药物常见分类的扩展。