Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
J Hand Surg Am. 2020 Jun;45(6):512-517. doi: 10.1016/j.jhsa.2020.02.016. Epub 2020 Apr 13.
To clarify the sensitivity, specificity, and interrater reliability of the scratch collapse test for carpal tunnel syndrome (CTS) and cubital tunnel syndrome, using blinded observers in a general patient population.
Ninety-two subjects were recruited from all patients referred for electrodiagnostic studies for upper extremity symptoms that were thought to be related to an entrapment mononeuropathy. The scratch collapse test was performed twice on each patient, once by the resident and once by a nerve conduction technician. Both observers were blinded to all aspects of the patient's presentation. Sensitivity and specificity for the scratch collapse test were calculated twice, once using electrodiagnostic testing results and a second time using a validated clinical tool (the CTS-6) as the reference standard. The interrater reliability was also calculated.
Using electrodiagnostic criteria as a reference standard, the scratch collapse test had a sensitivity of 7% and a specificity of 78% for CTS. Using clinical criteria as a reference standard, the test had a sensitivity of 15% and a specificity of 87%. For cubital tunnel syndrome, the sensitivity was 10% and the specificity was 90%. For the resident/technician 1, kappa was -0.025 (worse than chance alone). For the resident/technician 2, kappa was 0.211 (fair strength of agreement).
The sensitivity of the scratch collapse test for CTS and cubital tunnel syndrome was lower than that found in other studies, regardless of whether a clinical or an electrodiagnostic reference standard was used. The specificity was high. Overall interrater agreement was lower than previously reported. These results call into question the sensitivity and interrater reliability of the scratch collapse test for CTS and cubital tunnel syndrome.
TYPE OF STUDY/LEVEL OF EVIDENCE: Diagnostic II.
在一般患者人群中,通过盲法观察者,明确挠刮试验诊断腕管综合征(CTS)和肘管综合征的敏感性、特异性和组内一致性。
从所有因上肢症状而被转诊进行电诊断研究的患者中招募了 92 名患者,这些症状被认为与单神经受压有关。对每位患者进行两次挠刮试验,一次由住院医师进行,一次由神经传导技术员进行。两位观察者均对患者的所有表现均不知情。使用电诊断测试结果和经过验证的临床工具(CTS-6)作为参考标准,两次计算挠刮试验的敏感性和特异性。还计算了组内一致性。
使用电诊断标准作为参考标准,挠刮试验对 CTS 的敏感性为 7%,特异性为 78%。使用临床标准作为参考标准,该试验的敏感性为 15%,特异性为 87%。对于肘管综合征,敏感性为 10%,特异性为 90%。对于住院医师/技术员 1,κ 值为-0.025(比单独机遇差)。对于住院医师/技术员 2,κ 值为 0.211(一致性适度)。
无论使用临床还是电诊断参考标准,挠刮试验对 CTS 和肘管综合征的敏感性均低于其他研究,特异性较高。总体组内一致性低于之前的报道。这些结果对挠刮试验诊断 CTS 和肘管综合征的敏感性和组内一致性提出了质疑。
研究类型/证据水平:诊断 II 级。