Department of Diabetes and Metabolism, The Royal London Hospital, London, UK.
Department of Diabetes and Metabolism, The Royal London Hospital, London, UK.
Clin Oncol (R Coll Radiol). 2020 Sep;32(9):579-590. doi: 10.1016/j.clon.2020.03.012. Epub 2020 Apr 13.
Diabetes and cancer are common conditions highly prevalent in the general population. The co-existence of diabetes and cancer in a patient is therefore not unexpected. Diabetes increases the risk of mortality from cancer and morbidity from the treatment of cancer. Furthermore, many cancer chemotherapeutic regimens increase glucose levels, especially those involving glucocorticoids. Many clinical oncologists will deal with patients with diabetes in their clinical work, and some working knowledge of diabetes diagnosis and management is helpful when managing such patients. This overview aims to summarise the clinical diagnosis and management of diabetes, review the potential links between diabetes and cancer, and provide some practical guidance on the management of hyperglycaemia in patients undergoing cancer therapy.
糖尿病和癌症是在普通人群中非常普遍的常见疾病。因此,患者同时患有糖尿病和癌症并不罕见。糖尿病会增加癌症死亡率和癌症治疗发病率。此外,许多癌症化疗方案会升高血糖水平,特别是那些涉及糖皮质激素的方案。许多临床肿瘤学家在临床工作中会接触到患有糖尿病的患者,因此在管理这些患者时,了解一些糖尿病诊断和管理的基本知识是有帮助的。本篇综述旨在总结糖尿病的临床诊断和管理,回顾糖尿病和癌症之间的潜在联系,并提供一些有关癌症治疗患者高血糖管理的实用指导。