• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

减瘤性肾切除术后转移性肾细胞癌的自发消退:一例报告

Spontaneous regression of metastatic renal cell carcinoma after cytoreductive nephrectomy: A case report.

作者信息

Muraoka Kuniyasu, Nishikawa Yuri, Isoyama Tadahiro

机构信息

Department of Urology, Tottori Prefectural Central Hospital, 730 Ezu, Tottori, 680-0901, Japan.

出版信息

Urol Case Rep. 2020 Apr 2;31:101179. doi: 10.1016/j.eucr.2020.101179. eCollection 2020 Jul.

DOI:10.1016/j.eucr.2020.101179
PMID:32300531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7152652/
Abstract

We herein report a case involving a 59-year-old man with right lung and mediastinal lymph node metastases from renal cell carcinoma. After cytoreductive nephrectomy without neoadjuvant therapy, he achieved spontaneous regression. The regression was maintained 3 years after the operation. We immunohistochemically examined the surgical specimens and considered the possible mechanism underlying this phenomenon.

摘要

我们在此报告一例涉及一名59岁男性的病例,该患者患有肾细胞癌伴右肺和纵隔淋巴结转移。在未进行新辅助治疗的情况下进行了减瘤性肾切除术后,他实现了自发缓解。术后3年缓解状态持续存在。我们对手术标本进行了免疫组化检查,并探讨了这一现象背后可能的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/5c5822695e6a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/3ffff765e09a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/9e052139effc/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/5c5822695e6a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/3ffff765e09a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/9e052139effc/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4c/7152652/5c5822695e6a/gr3.jpg

相似文献

1
Spontaneous regression of metastatic renal cell carcinoma after cytoreductive nephrectomy: A case report.减瘤性肾切除术后转移性肾细胞癌的自发消退:一例报告
Urol Case Rep. 2020 Apr 2;31:101179. doi: 10.1016/j.eucr.2020.101179. eCollection 2020 Jul.
2
Lymph Node Dissection is Not Associated with Improved Survival among Patients Undergoing Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma: A Propensity Score Based Analysis.淋巴结清扫术与接受细胞减灭性肾切除术治疗转移性肾细胞癌患者的生存改善无关:基于倾向评分的分析。
J Urol. 2017 Mar;197(3 Pt 1):574-579. doi: 10.1016/j.juro.2016.09.074. Epub 2016 Sep 20.
3
Spontaneous regression of multiple pulmonary metastases accompanied by normalization of serum immune markers following cytoreductive nephrectomy in a patient with clear-cell renal cell carcinoma.一名透明细胞肾细胞癌患者在进行减瘤性肾切除术后,肺部多处转移灶出现自发消退,同时血清免疫标志物恢复正常。
IJU Case Rep. 2020 Dec 26;4(2):95-99. doi: 10.1002/iju5.12252. eCollection 2021 Mar.
4
Solitary Metastasis in the Mediastinal Lymph Node After Radical Nephrectomy for Clear Cell Renal Cell Carcinoma: A Case Report and Literature Review.根治性肾切除术后透明细胞肾细胞癌纵隔淋巴结孤立转移:一例报告及文献复习
Front Oncol. 2020 Dec 17;10:593142. doi: 10.3389/fonc.2020.593142. eCollection 2020.
5
A case of metastatic renal cell carcinoma successfully treated with deferred cytoreductive nephrectomy following lenvatinib plus pembrolizumab combination therapy.一例在乐伐替尼联合帕博利珠单抗治疗后接受延迟减瘤性肾切除术成功治疗的转移性肾细胞癌病例。
IJU Case Rep. 2023 Mar 19;6(3):185-189. doi: 10.1002/iju5.12584. eCollection 2023 May.
6
Delayed Cytoreductive Nephrectomy Following Three Years of Targeted Therapy for Metastatic Renal Cell Carcinoma.转移性肾细胞癌靶向治疗三年后延迟性细胞减灭性肾切除术
Curr Urol. 2017 Jan;9(4):202-208. doi: 10.1159/000447141. Epub 2016 Dec 26.
7
A case of metastatic Xp11.2 translocation renal cell carcinoma successfully managed by cytoreductive nephrectomy followed by axitinib therapy.一例经减瘤性肾切除术联合阿昔替尼治疗成功的Xp11.2易位转移性肾细胞癌病例。
Mol Clin Oncol. 2017 Mar;6(3):362-364. doi: 10.3892/mco.2017.1142. Epub 2017 Jan 31.
8
Deliberation on Deferred Cytoreductive Nephrectomy and Postoperative Treatment for Advanced Renal Cell Carcinoma: A Case Report.晚期肾细胞癌延迟性细胞减灭性肾切除术及术后治疗的探讨:一例报告
Case Rep Oncol. 2022 Nov 8;15(3):1014-1020. doi: 10.1159/000527089. eCollection 2022 Sep-Dec.
9
Cytoreductive Nephrectomy Following Immunotherapy-Base Treatment in Metastatic Renal Cell Carcinoma: A Case Series and Review of Current Literature.免疫治疗基础治疗后行细胞减积性肾切除术治疗转移性肾细胞癌:病例系列及文献复习。
Curr Oncol. 2021 May 20;28(3):1921-1926. doi: 10.3390/curroncol28030178.
10
Comparative Survival following Initial Cytoreductive Nephrectomy versus Initial Targeted Therapy for Metastatic Renal Cell Carcinoma.初始细胞减灭性肾切除术与初始靶向治疗转移性肾细胞癌的生存比较。
J Urol. 2018 Sep;200(3):528-534. doi: 10.1016/j.juro.2018.03.077. Epub 2018 Mar 21.

引用本文的文献

1
Delayed Abscopal Response 3 Years After Robotic Stereotactic Body Radiation Therapy for Renal Cell Carcinoma: A Case Report.机器人立体定向体部放射治疗肾细胞癌3年后的延迟远隔效应:一例报告
Cancer Rep (Hoboken). 2025 May;8(5):e70229. doi: 10.1002/cnr2.70229.
2
Transition to Targeted Therapies Improved the Prognosis and Increased the Utilization of Medical Treatments among Patients with Synchronous Metastatic Renal Cell Cancer.同步转移性肾细胞癌患者向靶向治疗的转变改善了预后并增加了医疗治疗的利用。
Int J Surg Oncol. 2021 Aug 12;2021:5237695. doi: 10.1155/2021/5237695. eCollection 2021.

本文引用的文献

1
Prognostic and Predictive Value of Tumor-infiltrating Leukocytes and of Immune Checkpoint Molecules PD1 and PDL1 in Clear Cell Renal Cell Carcinoma.肿瘤浸润白细胞以及免疫检查点分子PD1和PDL1在透明细胞肾细胞癌中的预后和预测价值
Transl Oncol. 2020 Feb;13(2):336-345. doi: 10.1016/j.tranon.2019.11.002. Epub 2019 Dec 24.
2
Complete response to perioperative treatment using nivolumab for metastatic renal cell carcinoma: A case report.纳武单抗用于转移性肾细胞癌围手术期治疗的完全缓解:一例报告
Urol Case Rep. 2019 Jan 30;24:100839. doi: 10.1016/j.eucr.2019.100839. eCollection 2019 May.
3
Systematic Review of the Role of Cytoreductive Nephrectomy in the Targeted Therapy Era and Beyond: An Individualized Approach to Metastatic Renal Cell Carcinoma.
系统评价细胞减积性肾切除术在靶向治疗时代及以后的作用:转移性肾细胞癌的个体化治疗方法。
Eur Urol. 2019 Jan;75(1):111-128. doi: 10.1016/j.eururo.2018.09.016. Epub 2018 Oct 25.
4
SPONTANEOUS REGRESSION OF CANCER.癌症的自发消退
Ann N Y Acad Sci. 1964 Apr 2;114:721-35.
5
Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial.根治性肾切除术联合基于干扰素-α的免疫疗法与单纯干扰素-α治疗转移性肾细胞癌的随机对照试验
Lancet. 2001 Sep 22;358(9286):966-70. doi: 10.1016/s0140-6736(01)06103-7.