Eisenhardt A, Ohlmann C-H, Doehn C
Praxiskliniken Urologie Rhein Ruhr, Schulstr. 11, 45468, Mülheim an der Ruhr, Deutschland.
Klinik und Poliklinik für Urologie, Kinderurologie und Uroonkologie, Universitätsklinikum Essen, Essen, Deutschland.
Urologe A. 2020 May;59(5):533-543. doi: 10.1007/s00120-020-01182-0.
Systemic therapy in uro-oncology is currently undergoing major changes. In the past, drug therapies only showed good treatment results in metastasized testicular tumors. New developments indicate that an improved understanding of tumor biology will lead to targeted treatment strategies for metastatic prostate, urothelial and renal cell carcinoma. In the following article, we summarize the practice-relevant innovations in systemic therapy in the guidelines on prostate cancer, transitional cell carcinoma of the bladder and renal cell carcinoma.
泌尿肿瘤学的全身治疗目前正在经历重大变革。过去,药物治疗仅在转移性睾丸肿瘤中显示出良好的治疗效果。新的进展表明,对肿瘤生物学的进一步了解将为转移性前列腺癌、尿路上皮癌和肾细胞癌带来靶向治疗策略。在接下来的文章中,我们总结了前列腺癌、膀胱移行细胞癌和肾细胞癌指南中全身治疗与临床实践相关的创新内容。