Sunde A, Kahn J A, Molne K
Department of Obstetrics and Gynaecology, University Hospital, Trondheim, Norway.
Hum Reprod. 1988 Oct;3 Suppl 2:69-73. doi: 10.1093/humrep/3.suppl_2.69.
This report summarizes the data collected in the European Collaborative Report on intrauterine insemination (IUI) with pretreated sperm. A questionnaire concerning methods and results of IUI was sent to European infertility clinics and evaluable data were obtained from 29 of these clinics. A total of 196 pregnancies was reported from a total of 20 clinics. Pregnancy rates per treatment cycle were on average 7.4% of all male infertility, 10.8% for infertility due to hostile cervical mucus and 12.9% for idiopathic infertility, giving an overall pregnancy rate per treatment cycle of 8.4%. The clinical abortion rate was on average 12.2%. The mean number of years of primary infertility in the patient group of the clinics reporting pregnancies was 4.8 years and the mean number of years of primary infertility in the patient group conceiving was 5.2 years. A total of 127 births was reported with a sex ratio (male/female) of 0.512. One congenital malformation was reported. In many clinics, treatment of male infertility with IVF or IUI gave comparable results per treatment cycle. No single factor in the procedure for performing IUI was identified accounting for the different pregnancy rates obtained in the clinics included in this study.
本报告总结了欧洲关于经预处理精子宫腔内人工授精（IUI）的协作报告中收集的数据。一份关于IUI方法和结果的调查问卷被发送至欧洲不孕不育诊所，从其中29家诊所获得了可评估的数据。20家诊所共报告了196例妊娠。每个治疗周期的妊娠率在所有男性不育症中平均为7.4%，因宫颈黏液异常导致的不育症为10.8%，特发性不育症为12.9%，每个治疗周期的总体妊娠率为8.4%。临床流产率平均为12.2%。报告有妊娠的诊所患者组原发性不孕的平均年限为4.8年，受孕患者组原发性不孕的平均年限为5.2年。共报告了127例分娩，男女比例为0.512。报告了1例先天性畸形。在许多诊所，用体外受精（IVF）或IUI治疗男性不育症，每个治疗周期的结果相当。在本研究纳入的诊所中，未发现IUI操作中的单一因素能解释所获得的不同妊娠率。
