Frontier Institute of Science and Technology (FIST), Xi'an Jiaotong University, Xi'an, 710049, P.R. China.
Departement of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710061, P. R. China.
ChemSusChem. 2020 Jun 8;13(11):2876-2893. doi: 10.1002/cssc.202000778. Epub 2020 May 20.
To achieve a safe, efficient, and sustainable (even fully automated) production for the continuous-flow hydrogenation reactions, which is among the most often used reactions in chemical synthesis, new catalyst types and immobilization methods as well as flow reactors and technologies have been developed over the last years; in addition, these approaches have been combined with new and transformational technologies in other fields such as artificial intelligence. Thus, attention from academic and industry practitioners has increasingly focused on improving the performance of hydrogenation in flow mode by reducing the reaction times, increasing selectivities, and achieve safe operation. This Minireview aims to summarize the most recent research results on this topic with focus on the advantages, current limitations, and future directions of flow chemistry.
为了实现连续流氢化反应的安全、高效和可持续（甚至全自动）生产，这是化学合成中最常用的反应之一，近年来开发了新型催化剂类型和固定化方法以及流动反应器和技术；此外，这些方法还与人工智能等其他领域的新技术相结合。因此，学术界和工业界越来越关注通过缩短反应时间、提高选择性和实现安全操作来提高流动模式下氢化的性能。这篇综述旨在总结该主题的最新研究成果，重点关注流动化学的优势、当前限制和未来方向。
