Department of Neurology, Odense University Hospital.
Department of Neurology, Odense University Hospital,, Neurology Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Epileptic Disord. 2020 Apr 1;22(2):225-228. doi: 10.1684/epd.2020.1148.
Transient epileptic amnesia (TEA) is a distinct syndrome affecting middle-aged persons without concurrent brain disease or disposition to epileptic seizures. Seizures are characterized by amnesia, usually lasting less than one hour, and interictal memory deficits that are common. Effective antiseizure treatment is usually rapid in patients with TEA, which underlines the need for prompt diagnosis. Here, we report a 58-year-old male patient with recurrent episodes of antero- and retrograde amnesia. MRI was normal and diagnosis was made using long-term EEG (27 hours), revealing 10 right-sided temporal lobe seizures with subtle clinical symptoms lasting up to 86 seconds. Details of the video-EEG are presented. Treatment with levetiracetam resulted in complete recovery and seizure freedom that was confirmed on a second long-term EEG. Given the favourable outcome with antiseizure treatment, our case study illustrates the role of long-term EEG monitoring in patients with recurrent transient amnesia to establish a correct diagnosis [Published with video sequence].
短暂性癫痫性遗忘症（TEA）是一种特殊的综合征，影响中年人群，无并发脑部疾病或癫痫发作倾向。发作的特征是遗忘症，通常持续不到一小时，且发作间期记忆缺陷常见。TEA 患者的有效抗癫痫治疗通常迅速，这强调了及时诊断的必要性。在这里，我们报告了一例 58 岁男性患者，反复出现顺行性和逆行性遗忘症。MRI 正常，使用长程 EEG（27 小时）诊断，显示 10 次右侧颞叶癫痫发作，具有轻微的临床症状，持续长达 86 秒。呈现了视频-EEG 的详细信息。左乙拉西坦治疗后完全恢复，第二次长程 EEG 证实无癫痫发作。鉴于抗癫痫治疗的良好结果，我们的病例研究说明了在复发性短暂性遗忘症患者中进行长程 EEG 监测以建立正确诊断的作用[发表时带有视频序列]。
