Factors affecting poor performance and scours in preruminant calves fed corn oil.

A 4-wk study with 12 3-d-old calves compared the effect of feeding tallow, corn oil, or corn oil plus aspirin on calf performance, feed utilization, incidence of scours, and composition of blood plasma lipids. Aspirin treatment was to inhibit a possible role of prostaglandins in promoting scours. Calves given both corn oil treatments had lower average daily gain, feed efficiency, and higher incidence of scours than those fed tallow. Unexpectedly, corn oil produced appreciably less scours in calves than encountered in previous studies. This appeared to be related to the fat dispersion method used here, which produced much smaller fat globules (less than 1 micron vs. 10 to 20 microns). Over-production of prostaglandins from corn oil was not a causative factor in scours development. Arachidonic acid and other linoleic acid prostaglandin precursors in blood plasma cholesteryl esters and phosphatidylcholine were reduced by dietary corn oil. Aspirin, a potent inhibitor of prostaglandin biosynthesis, was ineffective in reducing scours.