Gleysteen J J, Droege E A
Surgical Service, Zablocki Veterans Administration Medical Center, Milwaukee, Wisconsin.
J Clin Gastroenterol. 1988 Dec;10(6):619-22. doi: 10.1097/00004836-198812000-00008.
Forty-nine patients with chronic pyloroduodenal ulcer stenosis were treated surgically in our hospitals between 1977 and 1985. Three operations were used: 16 patients had a proximal gastric vagotomy-pyloroplasty (PGV-P); 26 had a vagotomy-antrectomy (V-A); and seven had a truncal vagotomy-pyloroplasty (TV-P). Historical data and preparations for operation were similar in each group. We compared the early clinical outcome in these patients. Two patients died after V-A and one died after TV-P. Five patients were reoperated: V-A (three patients), PGV-P and TV-P (one patient each). Delayed gastric emptying with nonoperative resolution (DGE) occurred in nine patients after V-A and in two patients after TV-P. Preoperative gastric suction and parenteral nutrition did not avoid DGE or affect timing of return to a general diet. A solid diet was resumed earlier (p less than 0.01) after PGV-P (5 +/- 1 days) than after V-A (13 +/- 8 days) or TV-P (9 +/- 2 days). Ninety-four percent of patients after PGV-P had an uneventful recovery, compared with 46 and 43% after V-A and TV-P, respectively. Among the variables measured, operative choice of PGV-P expedited early surgical recovery of patients with chronic ulcer stenosis.
1977年至1985年间,我院对49例慢性幽门十二指肠溃疡狭窄患者进行了手术治疗。采用了三种手术方式:16例患者接受了近端胃迷走神经切断术-幽门成形术(PGV-P);26例接受了迷走神经切断术-胃窦切除术(V-A);7例接受了全胃迷走神经切断术-幽门成形术(TV-P)。每组患者的病史资料和术前准备情况相似。我们比较了这些患者的早期临床结局。V-A术后有2例患者死亡,TV-P术后有1例患者死亡。5例患者接受了再次手术:V-A(3例患者)、PGV-P和TV-P各1例。V-A术后有9例患者出现了非手术治疗可缓解的胃排空延迟(DGE),TV-P术后有2例患者出现该情况。术前胃肠减压和肠外营养未能避免DGE,也未影响恢复正常饮食的时间。PGV-P术后恢复固体饮食的时间(5±1天)比V-A(13±8天)或TV-P(9±2天)更早(p<0.01)。PGV-P术后94%的患者恢复顺利,相比之下,V-A和TV-P术后分别为46%和43%。在所测量的变量中,对于慢性溃疡狭窄患者,选择PGV-P手术可加快早期手术恢复。